I have been on off mirtazapine for probably 10/12 years as starting getting very low ,as time went on began getting depressed, but was worried about trying something new ,so Dr kept trying different doses, only thing about mirtazapine was good for sleeping, I weaned myself about 10 months ago, fine for while ,then few weeks ago began to feeling down again,knowing then needed to see someone,which I did,Dr was very helpful, he went long way through my records and realized mirtazapine wasn’t for again, so recommended sertraline,explaining 25mg for week,then 50ml which I start tonight,I’m hoping after few more nights sleeping will get better, as he said to get in touch 5 weeks. Any helpful information back be great.