Hello,
"Avascular necrosis (AVN) of the femoral head is a type of aseptic osteonecrosis, which is caused disruption of the blood supply to the proximal femur, which results in osteocyte death. AVN may occur due to ischemia developing on a traumatic or non-traumatic background. The most common etiological factors include treatment with corticosteroids, fractures, dislocation of the hip joint, and alcohol abuse. It typically affects physically active people aged between 20 and 40 years. Between 10,000 and 20,000 new cases of AVN of the femoral head are diagnosed in the United States (US) each year. In the United Kingdom, it is the third most common reason for total hip replacement (THR) in patients under 50 years of age."
Source: National Library of Medicine
National Center for Biotechnology Information
"Cause of Osteonecrosis
Osteonecrosis happens when the blood supply to part of a bone is disrupted, depriving bone tissue of essential nutrients and oxygen. If the affected part of the bone is small and not subject to major weight-bearing forces, it may not cause a problem or the body’s repair processes may be able to rebuild the damaged area. But in most cases, the repair mechanisms do not work and the bone erodes or develops fractures; eventually, it may break down and collapse.
In traumatic osteonecrosis, which develops from an injury, the loss of blood flow is likely due to damage to blood vessels. The reasons for the loss of blood supply are less clear in nontraumatic cases, but may be due to blood clots blocking the circulation or elevated pressure within the bone constricting the vessels and decreasing blood flow.
While the underlying causes of nontraumatic osteonecrosis are not fully understood, scientists believe that genetics, along with other factors—such as alcohol overconsumption, certain medications, or other diseases--may play a role."
Source: National Institute of Arthritis and Musculoskeletal and
Skin Diseases
An official website of the United States Government
Regards, masso