Has anyone else had digestion problems while taking cymbalta? I started out taking 30mg for chronic?

I was prescribed Cymbalta 8 years ago for chronic pain. After 5 years of taking it I began having extreme stomach pain with gas, bloating, diarrhea, constipation, hot flashes, nausea & the list goes on. I haven’t been able to leave my house for 3 years except for Dr appts and have missed many of them because of these symptoms. Dr told me I had IBS and gave me smooth muscle relaxants which did nothing. Pepto, mylanta, kaopectate & all other over the counter meds didn’t touch it. I’ve been taking multiple other medications for pain including opioids, muscle relaxants, lyrica & elavil. I have stopped the opioids and muscle relaxants along with several foods thinking that was the cause. I stumbled upon this thread and decided to try to stop the cymbalta. It’s been 3 days and I haven’t had an attack after they had progressed to happening everyday. I hope and pray I can stay off this medication and that’s it’s been the culprit all along. I’ll keep you updated.

I'm 75 years old. I was diagnosed with Fibro last December. I was prescribed Duloxetine 30 mg. After about a month, I called my doctor and told him it wasn't helping much, so he upped the dosage to 60. After about 2 months, I started with digestion problems. It was alternate constipation and diarrhea. I stopped taking Celebrex with Duloxetine thinking it might help. Now, all I have is regular diarrhea, especially in the morning. I am afraid to go anywhere in the morning - even church. I was wondering if lowering my Duloxetine would help. Trying to decide what to eat is a nightmare; I've lost 9 lbs. in 2 months.

Hi I took cymbalta for 4 days and had severe diarrhea bad headaches felt horrible I didnt eat much because I was so nausea

I suffer from what started as SAD when I was a teen that morphed (as predicted by my psychiatrist) into full-blown severe depressive disorder all year round. Winters (the "dark season") are still WORST for me. I am a max dose, 60mg, of Paxil at this point. We tried to add Abilify and 1/2 dose had me bouncing off the walls. When I was diagnosed with fibrymyalgia, we tried to move me from Paxil to Cymbalta. At 1/2 dose of each, the Cymbalta caused me such serious constipation, despite drinking a ton of prune juice (gag!) with Miralax (Restoralax in Canada) that on the 7th day I went to the ER, afraid I was impacted. Day 8 I finally "went." We'd stopped the Cymbalta right away, but if you suffer from IBS, which I do (and it swings both ways) Cymbalta can really wreak havoc. For me, horrible constipation.

Hi, I just started it 4 days back. I was on Zoloft and my doc suggested me to add cymbalta 20mg to care nerve pain (Pain in Neck and Lower back). Zoloft helped me with depression but never helped me in body pains. First 4 days has some benefits and huge side effects. I am having severe stomach upset and my eye are blur. (All Low Blood Pressure symptoms) My eyes looks like swollen and sensation issues. On the positive side on day one itself it stopped my neck and back pain.
But the tough thing is I feel like falling my head spins all the time. Its horrible to bare. As your post is few years back just checking how did Cymbalta helped you in long turn???

Yes, my wife has been on Cymbalta for about 3-4 months and had to stop due to constipation and over lethargy and apathy and sexual side effects. Cymbalta induced constipation caused hemorrhoids for her as well. She has been struggling now for a month ever since she stopped.
Also, Cymbalta has severe and very unpleasant withdrawal effects and the manufacturer does not lower dose make pills that one can use to gradualy step down when tapering. Avalialble Cymbalat dosage is not well suitable for a long term taper.
Googe Cymbalta withdrawals before you go too long down this path

Diarrhea is a common side effect that will subside with continued use. Be sure to drink plenty of fluids that have electrolytes in them such as PowerAde and give the Cymbalta a few weeks before making a decision whether to continue or not.

If the cymbalta is working, try over-the-counter diarrhea medication. It's better to be pain-free and take medication for diarrehea, in my opinion. But, it is your decision. Being in pain is not fun... Good luck!