Ive been on 10mg amitriptyline once a night for about 5 months for ibs symptoms while ive been on this medication ive found myself feeling very low very tired and started getting anxiety and panic attacks from bowhere which id never ever experienced before and I heard and read online that amitriptyline can cause this. So I had my last ami 4 days ago and I already feel better within myself and have my first panic free day without needing a propranolol tablet for the first time in absolutely ages . Has anyone else had experience with this? Tia :)
Has anyone come off of 10mg amitriptyline after experiencing hightened anxiety whilst on it?
Question posted by cupcake2290 on 5 Sep 2013
Last updated on 24 April 2024
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
11 Answers
I have been taking Amitriptyline for 25+ years. I am now 73. I take the Rosemount brand which was prescribed by a Consultant Rheumatologist as I had severe arthritis in both hands. I was surprised to read that so many people have problems with anxiety taking this medicine. I take this for spinal and joint pain. The back pain improved after a spinal op 2019. I continue to take it for general pain relief, insomnia and mild and occasional anxiety. The usual dose is 10-25mgs; I have never experienced the severe symptoms detailed in most of these posts, quite the opposite. Surely if it is being taken for anxiety then those symptoms may prevail? Maybe raising the dose would help?
Currently I am trying to find an alternative, to Rosemount as there are (very) occasional stock problems. NB These are always local suppliers not the actual Rosemount factory here in the UK.
I was prescribed 25 miligrams if Amitriptyline for anxiety and panic attacks along with xanax and then bumped it down from 25 to 10 because I was having problems with my eyesight. As I have been down to the 10mg I wake up with anxiety and panic attacks daily. Some days crying half the day experiencing very bad depression. I found tge most informative website called surviving anti depressants . On that website is the best help that I have received about meds , what they do to your brain and help with tapering off . I also have been going to NA meetings to help me because I am convinced the side effects are very strong withdrawals from detoxing them and I am very scared . It has been really hard . I am only taking a 1/2 of a 1/2 of xanax in addition to these meds and was educated to first get of the amitriptyline first because it has a longer half life coming off . So thats where I am right now. I also pray alot as soon as I wake up.
Because the moment my brain realizes Im awake the trouble begins like clockwork. I pray thru the anxiety make myself wake uo and get out of bed even though I feel frozen. And I do not eat any sugar either or caffeine
I am just coming off of amitriptyline after about 5 years taking 10mg a day for back pain. It has been 2 weeks now and I have taken 2 trips to the hospital with body tremors and huge panic attacks and heart racing... they have told me it's not from coming off the drug and feel I am just having sever panic attacks which I have never experienced before in my life. This is terrible and I feel totally out of control. I don't know when I will have one of these attacks. My son in law who is a doctors says it would be very rare for me to still have these attacks after a couple of weeks. Actually the first week I was fine it was the end of the first week and the second week. Hoping this passes soon. I can't sleep at all feel tingling all over and nervousness is terrible. I am trying to take Benadryl to help me sleep. The hospital gave me an Ativan which calmed me down enough to get a few hours of sleep...
I will see a Naturopath this week to see if they can help with this as the Medical Doctors give you the drug and they say I don't know! This is a terrible drug!
Yes. I had the worst anxiety ever, and actually thought I was going to lose my mind. To make it worse, the doctor who prescribed the medicine never got back to me. I took myself off slowly. Going down to 5mg for 2 nights, one night, etc. However, I had to go to another doctor to get anti-anxiety meds to "reset my clock." I went on ativan. One hit of that and I was finally able to eat. In one week, I lost about 10 pounds because the anxiety was so bad, I couldn't eat nor sleep. I wish you luck, and my advice is to have a psychiatrist overlook medicines like this. They know them so much better than GIs.
I have taken amitriptyline 25mg for over 6 years ago every night at bedtime. For the last 2 weeks my heart rate has raced for no reason. My anxiety has been tenfold. I feel like the end of time is near. Now don't take it as suicidal feelings it's not that way. I'm not depressed or anything like that. I am on other antidepressants. I also have feelings about this medication for the past couple of weeks that I needed to do some research on it. It says do not stop it abruptly and it can cause a major heart attack. It also conflicts seriously with several of my other medications. Does any of you have any other medications that you find the amitriptyline messes with? I want to get off this medication as quick as I can but I want to do it safely
I m on ami was 25mg weaned down to 10mg doctor put me citalopram 20mg he s now stopped ami 10mg and upped citalopram to 30mg they interact with each other he said it s a prob so c how I go I was in all 4 2 years
Thanks everyone for these posts. I recently was put on amitriptyline 10mg for GI reasons. In the third week, I began to lose my appetite and became very anxious and experienced panic attacks like I never had before. In the 4th week, when I told my GI, she upped me to 20mg, but I was bouncing off the walls and extremely anxious. After 2 nights on 20mg, I came back down to 10mg. Seeking help, I called the GI and some psychiatrists; however, I have not had any return calls. I took myself down to 5mg for 2 nights, and then last night none. (I also checked with my pharmacist, who was helpful.) This morning, I am a little better, and will start back on 5mg of Lexapro tonight, possibly working up to 10mg. I never had problems on Lexapro.
So i think iv been on amitriptyline20mg about a year for chronic daily headache . I had awful sleep hangovers for months but i made it work as i worked evenings iv been sooo tired, i had chronic constipation. Would be 5 to 8 days delayed and I'd have to take strong laxatives to get relief and even then id have bad back pain the whole time from the pressure on my spine. This has finally wore off over about 9 months. And now im a constant emotional mess. I have panic attacks just about everyday I have constant bad thoughts when my mind isnt occupied. Im trying to be happy i have a wonderful life and its a lot better from the constant headaches id have for weeks at a time. Its a catch 22 really. I stop i go back to headaches i stay im a emotional mess. Has anyone got advice they can give me ?
I was on Amitriptyline 10mg for about a year but I stopped due to a lot of weight gain and I just couldn't get it off.
I was taking it for burning mouth syndrome, however since I have stopped I have had serious anxiety attacks, cant sleep at all, awake on the hour every hour, feel in a constant panic and have to leave a light on in bed its that bad., never suffered from anything like this in my life, now wondering if I should go back on them.
I was put on amitriptyline 25mg for mystery neuropathy in my legs. I tried to get off of it three months later. I was OK the first few days. About 2 weeks later I felt an anxiety and depression that I had never felt before. I couldn’t eat or sleep. My mind couldn’t rest. It was so strange. I finally went back on it because I was such as mess. I am going to definitely wean myself off slowly when I do decide to get off of this drug. If you ever see this, please let me know how you are feeling, because your reaction sound a lot like mine.
I wish I could help. The doctors tell me amitriptyline is not addictive, yet I’ve tried to get off it 3 times and can’t. I get so sick I start taking it again. It’s now on a list of drugs correlated with Alzheimer’s and I’ve been in it for 15-20 years for migraine prevention. I’ve got to get off of it. I went from 25mg to 20mg two days ago and I feel awful. My head hurts, my vision is screwy and I feel like a zombie. I’ve ordered Sam-e from Amazon and should have that in the next day or two. I’m hoping that if I supplement with Sam-e the withdrawal won’t be as severe. I can then either stay on the Sam-e or quit it over time. I’ve just got to get off amitriptyline. I don’t want Alzheimer’s.
I was prescribed to take 10-30mg amitriptyline every night to help with post infectious ibs symptoms. It has helped so much but not without side effects. At first I had very vivid and disturbing dreams, I'm really drowsy until about midday and I have gained weight. If it forget to take one I get mood swings too. I reallllly want to come off this now as it has been over 9 months - any tips/advice/survival strategies?
Molly
I have been on 5 to 10 mg of Amitriptyline for 20 years, presumably for fibromyalgia and CFS, but I don't think I have that. It was tiredness due to deficiency of iron and Vit D. I tolerated Amitrip well till I turned 47, but the day drowsiness, and some anxiety on this med were always there.
However, last two years I have been waking up feeling more anxious and feel more stressed out and also started feeling claustrophobic in very closed spaces.
I have tried getting off this medicine 5-6 times, but the withdrawal effects set in a day or two later--half hour sleep, half hour awake throughout the day.
Has anyone withdrawn? And what are the withdrawal effects?
Hi I was put on 10mg last year for anxiety and panic attacks I had during the night, also had trouble sleeping. It really really helped me sleep. Certainly did not give me panic attacks. Now a year later I want to come off, but slightly afraid, I will cut tabs in half to 5mg and see how it goes. Good luck to all
I was put on ami to help with my inability to sleep. Without ami, I am lucky to get 3 hours in a night and am a total zombie all day. The reason you can't sleep when you come off it is that in low doses, it's effectively a sleeping pill and you are stopping taking it, which will obviously have an effect on sleep. I'm sorry. I can't tell you how long that will last.
Hi! Just wondering how you got on after quitting the ami? I'm feeling much like you described and am pondering coming off :)
Hi, I have just come off of amitriptyline after taking 25mg every night. I have stopped for 2 weeks ,Like you I was so very tired all the time and awful feeling of anxiety! I feel ok now but waking up still too feeling very heavy chested and heart pounding! but I am not going to take anymore,I am not tired any more, and feel good throughout the day so hopefully these after effects will soon stop!
10 mg. is the lower dosis in this class of drug. Yes you will feel tire as side effects. I just tapered off of 10 mg. but my doc. recommended a different antidepressant. In week of your last pill you will be fine. As your doc. for a new one if you need it. Regards,
Alcon
Hi Tia-
I take the amitrip for sleep 10mg. I am so gald you wrote in. I am trying to get off the amitrip because I kept thinking it may be causing me more anxiety, especially when I wake up. I am also fatigued.
Did you taper down or just quit? Did you have any withdrawal symptoms?
I am glad you are feeling better. I hope there are better meds for you IBS.
janie
Hi janie
I just quit taking it I was literally fallig asleep within an hour of taking it and no matter how long I slept I felt so tired the next day. I saw my dr and told her my reasons for quitting and she said as 10mg is such a low dose its fine to just stop as cutting down really wouldbt make a difference. I have been off of them for a week now and had no withdrawal ive honestly felt so much better and not obe panic attack! It was so bad I was panicing as soon as I woke up with no reason to id be hot heart racing shaking inside and have felt none of that since stopping. How long have you been on the ami ? Maybe you could try taking it every other night for a week then every 3rd night and so on if you are worried about coming off of them .
Tia
Hi Tia-
I get the same wake anxiety you got. It is horrible. I wake up sweaty, shaky and full of anxiety. I am sorry you had to experience that. I am glad to know that amtriptyline may be the cause of my morning wake up anxiety. I am going to start taking 1/2 of a 10 mg for a few days and see if I can get off of it to see if that is what is causing the morning anxiety. Thank you for posting your experience it helped me :) Hope you find a med that works for your IBS.
janie
I have been taking amitripoline for 3 weeks now I went from 10 mg the first week and the last 2 weeks ive been taking 20 mg a hour before bedtime to help me sleep I have been having nightmares very bad ones I scream in my dreams to wake myself up so is this common and if I decide to stop will I have withdraws from it
I have been having the same issue with dreams and anxiety. I have also been screaming in my sleep to wake myself up, so glad I am not the only one. My OCD tendencies and anxiety were far worse on this drug at 10 mg. My doctor switched me to Effexor this week and said it was fine to completely stop Elavil since the dosage was so low.
I take 3 to 5 of these pills, 10 mgs each, at night along with Clonazepam, I dropped Ambien because it seems I was taking so much at night to sleep. After getting a letter from my insurance carrier saying there are many side affects, I took a look. I was astounded! HOW do I get off this stuff? Thanks for any help. Sincerely, Gale
Hi Gale-
Not sure you are trying to get off the Amitrip and or the Clonazepam too?
It is best to tapper off the Amitrip, maybe cutting it back 10 mg at a time per week. Check with your doctor. The C-pam is a benzo and you can develop a dependency to it. It may be harder to stop if you are going to. Again check with your doctor.
Hope it all works out.
I’m on 20 mg and have been for years for migraines: I need to get off it because of high panic attacks:
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- Amitriptyline uses and safety info
- Amitriptyline prescribing info & package insert (for Health Professionals)
- Side effects of Amitriptyline (detailed)
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