Does 25mg sertraline cause more anxiety 2 weeks in?

Pam, have you told your doctor about the panic attacks? An increase in anxiety, in fact, everything you described are common for some users for the first few weeks but panic attacks aren't. Your doctor may be able to prescribe a mild sedative to use very briefly until your system regulates.
"Poop out" is something that occurs when someone has been on an antidepressant for an extended period of time, many months or usually years. For some unknown reason the drug slowly becomes ineffective.
Have you noticed any positive effects? Does your mood seem any lighter?
You'll need to trust your gut on this because there's no simple answer other than that you are aware of your progress, or lack of. If you're not satisfied with where you're at then it may be time for an increase. The recommended protocol is for increases (if needed) at intervals of at least a week.
But first of all get this panic attack situation under control... you can't live like that and you need to get some restful sleep.

Hello,
Poop out; become less effective. Are usually common with most antidepressants when taken long term. In short, taken for over a year or more. But, you only have taken it for 2 weeks while noticing few improvements. I’ll suggest you give it time, as the medication is starting to get adjusted to your metabolism. SSRI’s normally take a while to become fully effective(within 6-8 weeks). Moreover, These medications work to alter brain chemistry so it’s a process that takes time, not even a week but months. Also, the therapeutic dose for Zoloft is 25-200mg, so you still have a lot of room to tweak the dose. If you’re hesitant to up the dose to 50mg. You can then ask your doctor to prescribe a short term medication to help you during these rough times until Zoloft(sertraline) kick in.

But, personally speaking I think you should give 50mg a shot.

I hope you get better soon.

Tyrese