Skip to main content

Children's NyQuil Cold and Cough

Generic name: chlorpheniramine and dextromethorphan [ klor-feh-NEER-a-meen-and-DEX-troe-meh-THOR-fan ]
Brand names: Children's NyQuil Cold and Cough, Coricidin HBP Cough and Cold, Cough And Cold, Robitussin Pediatric Cough and Cold Long-Acting, Scot-Tussin Sugar Free DM, ... show all 17 brands
Drug class: Upper respiratory combinations

Medically reviewed by Drugs.com on Aug 21, 2023. Written by Cerner Multum.

What is Children's NyQuil Cold and Cough?

Chlorpheniramine is an antihistamine. Dextromethorphan is a cough suppressant.

Children's NyQuil Cold and Cough is a combination medicine used to treat sneezing, runny nose, and cough caused by the common cold.

Children's NyQuil Cold and Cough may also be used for purposes not listed in this medication guide.

Children's NyQuil Cold and Cough side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Children's NyQuil Cold and Cough and call your doctor at once if you have severe drowsiness.

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

Common side effects of Children's NyQuil Cold and Cough may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not use cough or cold medicine to make a child sleepy.

Before taking this medicine

Do not use Children's NyQuil Cold and Cough if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medicine if you are allergic to chlorpheniramine or dextromethorphan.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

This medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

How should I take Children's NyQuil Cold and Cough?

Use exactly as directed on the label, or as prescribed by your doctor. Cough or cold medicine is only for short-term use until your symptoms clear up.

Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

You must chew the chewable tablet before you swallow it.

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

If you need surgery or medical tests, tell your surgeon or doctor if you are currently using this medicine.

Store at room temperature away from moisture and heat. Do not freeze.

Bromfed DM, Mucinex D, Promethazine VC with Codeine, Resperal-DM

What happens if I miss a dose?

Since cough or cold medicine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Children's NyQuil Cold and Cough?

Avoid driving or hazardous activity until you know how Children's NyQuil Cold and Cough will affect you. Your reactions could be impaired.

Avoid drinking alcohol while taking this medicine.

Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.

What other drugs will affect Children's NyQuil Cold and Cough?

Avoid using this medicine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures). Ask a doctor or pharmacist before using any other medication, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed in this medication guide.

Does chlorpheniramine/dextromethorphan interact with my other drugs?

Enter other medications to view a detailed interaction report.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.