Skip to main content

Promethazine User Reviews & Ratings (Page 2)

Brand names: Promethegan, Antinaus 50, Anergan 50, Adgan Phenadoz

Promethazine has an average rating of 7.2 out of 10 from a total of 373 reviews on Drugs.com. 65% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Promethazine

  • Anonymous
  • Taken for less than 1 month
  • July 31, 2015

Phenergan (promethazine) for Sedation "took one 25mg to help me sleep however the next day I felt awful like id been drugged just couldn't wake up this lasted all day.i wont be taking them again .my wife on the other hand takes them every night with no problems"

8 / 10
Was this helpful?YesNo
73 Report
  • Robin...
  • September 14, 2013

Phenergan (promethazine) for Nausea/Vomiting "I'm going through chemo (Taxol and Carboplatin) for ovarian cancer and Phenergan is great. I sometimes also take Zofran with it because they affect two totally different receptors causing the nausea and both together usually stops the ever present nausea."

10 / 10
Was this helpful?YesNo
84 Report
  • Kate
  • October 8, 2015

For Sedation "I take phernergan to help me sleep when I am run down or am needing that extra bit of sleep. It always knocks me out within an hour and I sleep like a baby! I struggle to wake up if I take a higher dosage but I wake up feeling refreshed and like I have slept for years! I recommend it to everyone who has trouble sleeping! I have also used it for hay fever but never really saw any remarkable changed in my allergy."

10 / 10
Was this helpful?YesNo
71 Report

Frequently asked questions

  • Momma...
  • June 20, 2014

Phenergan (promethazine) for Nausea/Vomiting "I have used this medication many times for nausea. It always helps quickly and completely. The only reason it does not get a perfect score is that it knocks me out! I'll be groggy for the rest of the day even with only one dose."

8 / 10
Was this helpful?YesNo
75 Report
  • Marie
  • Taken for 1 to 6 months
  • October 15, 2021

Phenergan (promethazine) for Sedation "I got these over 4-5 months. I started with 25 mg and ended up taking 2 every evening before bed. I started getting restless legs to the point where I had to wander around in my flat for hours like a zombie, and I sometimes only got a few hours of sleep. Also I began to get a bloody nose. Every morning I had to clean my nose with tissues, and the paper was always bloody. And the weight gain. Gained 15 kilos in that time. Right before I quit taking them I was miserable. Almost every night I had restless legs and I didn’t get much sleep. I have been off Phenergan since the beginning of August - I lost 7.6 kilos, my nose is just fine and I haven’t had one second with restless legs since. I’m back to having trouble falling a sleep but I definitely prefer that from all the horrible side effects."

1 / 10
Was this helpful?YesNo
26 Report

Are you taking this medicine?

  • Anonymous
  • November 4, 2015

Phenergan (promethazine) for Nausea/Vomiting "I was diagnosed with H Pylori and I was throwing up and nauseated every day for an entire month finally I was hospitalized and they gave me phenergran and God Bless the person who created this drug. Even now when I feel the slightest bit of nausea I take it and it'll knock me out and wake up feeling great"

10 / 10
Was this helpful?YesNo
63 Report
  • iron...
  • September 2, 2015

For Sedation "I am 53 year old male. I hurt my leg during an accident cliff jumping in the lake causing seveir leg damage.Doctor gave me Promethazine for nausea but I found that it really helps me sleep during pain epesodes from the operation. I have been taking 25 milligrams before sleeping. it's like placing a warm blanket over you, reduceing anxiety and coping with pain Allowing sleep."

Was this helpful?YesNo
63 Report
  • Laura...
  • May 13, 2013

Phenergan (promethazine) for Nausea/Vomiting "I have chronic pancreatitis and often have persistent nausea and vomiting. I have tried Zofran and a couple of other medications for this but none are as effective as Phenergan. Whether orally or I.V., it takes away the nausea. I have a GJ tube for enteral nutrition. Vomiting can cause the tube to twist and slide out of place so it's imperative to keep it under control. Phenergan does that for me. It also helps with the side effects from the painkillers I must take every day (oxycodone and Dilaudid). I don't know where I would be without it. Phenergan may be old school but it works for me better than any newer medicine."

9 / 10
Was this helpful?YesNo
74 Report
  • Marts
  • February 8, 2021

For Sedation "Experience on promethazine 25mg: slept undisturbed for a good 10 hours, found it super difficult to wake up, had to battle with my body to open my eyes and all I wanted to do was carry on sleeping. Kept on falling back asleep and waking up. Felt sedated and tired all day afterwards. Experience on 12.5mg (approx) splitting the pill in half: Slept for a long time, but still had negative side effects when waking up, I was very angry at my partner who tired to wake me up as I just wanted to carry on sleeping. Felt tired during the day also, but not as bad. I find that my optimal dose is about 1/3 of the tablet - it helps me sleep and the side effects of tiredness aren’t as bad in the morning. I do still experience agitation when woken up by someone else and would rather carry on sleeping but it isn’t as severe and usually after 20 mins or so I’m fully awake. The sedation/tiredness feeling during the day isn’t as prominent."

8 / 10
Was this helpful?YesNo
30 Report
  • Equal...
  • Taken for 1 to 6 months
  • May 22, 2020

For Sedation "I was prescribed promethazine for insomnia due to tinnitus. I took 25mg doses before bed when needed. Within about 30 minutes, I felt exceptionally drowsy and in a very relaxed state. Any anxiety I was experiencing was gone. I slept solidly for about 10 hours and then would wake up feeling pretty drowsy. I also cautiously took it when I had a chest infection and an asthma flare up. I got a great night's sleep and woke up feeling far less wheezy and with far less sputum. After six weeks of taking it nightly, it took a bit longer to make me sleepy and I woke up after less time. Then, suddenly, I found that taking the promethazine gave me extreme bouts of sleep apnoea. I repeatedly woke chocking and breathless. I immediately stopped taking the promethazine. I am now two days into withdrawal, waking up in the middle of the night feeling sweaty and finding it hard to go back to sleep. Overall, the drug really helped me but the apnoea and the withdrawal I had was a bit unpleasant."

8 / 10
Was this helpful?YesNo
33 Report
  • Anonymous
  • January 24, 2012

Phenergan (promethazine) for Opiate Adjunct "I am on opiate pain medication for a back injury from a car accident, and the opiates make me nauseated and vomit. Pain doc put me on 25mg Promethazine 3X a day and it works wonders! It will make you a little sleepy, but once you get used to it then that feeling goes away. And I've tried Tigan (Trimethobenzamide) which made nausea worse. Tried Zolfran (Ondansetron) which I hated because it taste nasty and that doesn't help when you are nauseated. I would HIGHLY recommend Promethazine for ANYONE who SUFFERS with nausea from opiates or has chronic nausea!"

10 / 10
Was this helpful?YesNo
76 Report
  • Anonymous
  • Taken for less than 1 month
  • January 20, 2016

For Sedation "I've always suffered with bad sleeping patterns and anxiety around stressful times such as exams or when I have a lot of deadlines, taking two of these (25mg each) knocks me out and means I don't have the bad anxiety dreams (that used to stop me from thinking straight) and now I get everything sorted the next day."

10 / 10
Was this helpful?YesNo
53 Report
  • Bethv...
  • July 30, 2016

For Nausea/Vomiting "I love this drug. I suffer with severe fear of vomiting and after getting prescribed it for insomnia I was over the moon. Not only does it help me sleep. It calms me down and stops all my anxiety nausea :) been taking it a few times a week for about a year and it's helped me out massively. Only bad point Is grogginess the next day but it's so worth it"

10 / 10
Was this helpful?YesNo
49 Report
  • scg
  • Taken for 1 to 6 months
  • June 12, 2021

Phenergan (promethazine) for Sedation "I don't know if I class myself as an insomniac but I usually wake up a load of times in the night which disturbs my sleep and makes me tired in the day so I decided to try Phenergan. This medication should really be taken just before you go to bed, I wouldn't recommend taking it while you're watching TV or anything because in my experience, you have to be trying to fall asleep for this to work. Even then, it's a horrible drug. 25mg is too little and I still wake up in the night a lot, 50mg is way too much and I'm pretty sure my throat closed up for a second in the middle of the night because I woke up gagging and I don't suffer from sleep apnoea so that was weird. Either way, any dosage of this stuff causes terrible daytime drowsiness the next day, I'm not sure if that's down to the half life of the medication or whether it is purely because it gives you really poor quality sleep."

1 / 10
Was this helpful?YesNo
23 Report
  • Uncon...
  • Taken for less than 1 month
  • February 23, 2018

For Nausea/Vomiting "Every time I get sick, whichever virus I contact seems to attack my stomach. No diarrhea or anything, Just constant puking. I would go to the clinic knowing what I wanted, which was promethazine, and after 3 hours and about $130, I get my promethazine prescription. My question is: Why is it a prescription drug in the 1st place? It's not abusive. Sure, it can make you sleepy, but so can Nyquil. My answer is the fact that it keeps clinics and a good amount of doctors in business. If people can cure themselves, what do we need to go to the doctor for? In more ways than good, our healthcare system has twice as many drawbacks than benefits for the people. Just think about it."

9 / 10
Was this helpful?YesNo
39 Report
  • atypi...
  • Taken for 5 to 10 years
  • May 4, 2020

For Nausea/Vomiting "For decades, I've dealt with nausea (with & without vomiting). At times it resembles motion sickness, occurring as a passenger in certain vehicles, but most commonly I simply experience an onset of nausea. It dates back to early childhood (now age 39). Two meds effectively treat it for me: ondansetron (Zofran) & promethazine (Phenergan). I opt for promethazine due to price & versatility. If I sense the onset of nausea, I take just 6.25mg (thanks to bi-scored tablets) & proactively treat it. Likewise, if I'm nauseated to the point of being unable to function, I can take 12.5, 18.75 or 25mg- depending on circumstance. I have no significant side effects. It can cause drowsiness (in me) but only sedates if I lie down to sleep. I've taken 25mg many times & gone about my day. I also find it helpful for certain allergies. Its versatile & I love that I can tailor the dose precisely & depend on it. I've been prescribed for a decade, though only find it necessary 5-7 times a month, on average."

9 / 10
Was this helpful?YesNo
28 Report
  • macca
  • March 9, 2020

Phenergan (promethazine) for Sedation "Phenergan is the best sedation I have seen... I find over 12.5 mg knocks me for " six ". Most of these medications are best when used sparingly , when needed. Taking sedation every night tells me a powerful anti psychotic may be a more suitable option."

9 / 10
Was this helpful?YesNo
29 Report
  • MamaB...
  • Taken for 1 to 6 months
  • January 14, 2020

For Nausea/Vomiting "This med is a lifesaver. I take 25mgs when I get super nauseous and it takes it away in 10 to 15 mins. Idk about the making you sleepy part because it doesn't do that to me. However, it gets a 10 on the nausea factor alone."

10 / 10
Was this helpful?YesNo
29 Report
  • Slaz
  • September 24, 2015

Phenergan (promethazine) for Nausea/Vomiting "I tried this medicine a day after I vomited three times and had that nausea feeling and that next day I vomited once in the morning but when I went to the medical centre they gave me the prescription for phenergan. I fell asleep instantly for two hours and a half and woke up refreshed and my stomach did not hurt for the rest of the day and I didn't vomit ever since. It's the best medicine for nausea and vomiting."

10 / 10
Was this helpful?YesNo
48 Report
  • mommy...
  • Taken for 1 to 6 months
  • August 28, 2015

For Nausea/Vomiting "This medicine saved my life I had severe nausea couldn't keep anything down. I was at the point where I thought this pregnancy would kill me but my doc introduced me to this medicine and it changed my life. I love it and I always keep it around"

10 / 10
Was this helpful?YesNo
48 Report
  • Jo...
  • Taken for 1 to 2 years
  • May 25, 2018

For Nausea/Vomiting "I love promethzine. It helps with my PMSing for nausea. I also have horrible emetophobia, definitely comes in handy. I also use it if I have sickness from the flu and motion sickness for planes. I high recommend this drug!"

10 / 10
Was this helpful?YesNo
35 Report
  • Sleep...
  • April 4, 2020

For Sedation "I have used Phenergan on and off for a few years for insomnia. They work extremely well. I take just 12 mg and that gives me six hours. If I take 1 25mg I am sleepy all morning and not terribly motivated to do much. However the down side is they make me terribly hungry. I am basically good at controlling my weight and appetite but on these l lose that control and seem to snack all day."

8 / 10
Was this helpful?YesNo
26 Report
  • Scott...
  • Taken for 1 to 6 months
  • October 28, 2018

For Sedation "Used this for the last 4/5 weeks. I tried this as it was a solution that I could get over the counter. I take 1 x 25mg per night (packaging says you can take up to 2 x 25mg) and I don’t have any side effects. Sleep deep, hear my alarm and I feel fine the next day. I have had other over the counter sleeping tablets and this is far best! HIGHLY RECOMMEND!!"

10 / 10
Was this helpful?YesNo
32 Report
  • Yanks
  • Taken for less than 1 month
  • March 9, 2017

Phenergan (promethazine) for Nausea/Vomiting "Has anyone experienced sadness after starting to take this drug. I am on 25mg for a few days and feel that it has helped with the nausea a little bit with the anxiety but it has made me sleep all day and feel sad. I normally have trouble getting onto strong meds such as anti depressants but I don't know if this is a case of this or something else. I am scared of becoming depressed."

8 / 10
Was this helpful?YesNo
38 Report
  • chezd...
  • Taken for 5 to 10 years
  • March 13, 2016

For Sedation "Great stuff. Best way to beat restless sleep patterns. Not up and down like a yoyo when I take. One. Use 1 25mg. Get sick of the silly questions at the pharmacy. Don't take it every night about 3 times a week."

10 / 10
Was this helpful?YesNo
42 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.