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Synthroid User Reviews & Ratings (Page 4)

Synthroid has an average rating of 6.1 out of 10 from a total of 189 reviews on Drugs.com. 51% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Synthroid

  • JaclynB
  • Taken for 5 to 10 years
  • August 7, 2019

For Hypothyroidism, After Thyroid Removal "Lately I have been experiencing flu like body pains. Feeling achy weak legs and arms. This medicine is ruining my life. Every time I increase the dosage even by small amounts I feel so nervous and withdrawn."

1 / 10
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  • Hopef...
  • October 18, 2013

For Hashimoto's disease "I was on this medication for about two weeks or so and within the first couple of days it made me feel extremely anxious and depressed. I felt as if I was not in control of my emotions. As if this was not bad enough I also felt an uncomfortable sensation in my neck and experienced trouble sleeping."

2 / 10
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  • Anonymous
  • April 12, 2016

For Hypothyroidism, After Thyroid Removal "I had my thyroid removed about 2 years ago. I weighed about 190. I was put on 125 mcg Synthroid right after the surgery. I lost about 20 pounds without trying at all. My dosage was increased to 175 mcg. I then started gaining weight. My endocrinologist increased my dosage to 200 mcg. My weight went up to 224 lbs. Never weighed so much before. I've been told by a couple of other doctors that the higher doses of Synthroid should cause weight loss, not gain. I am 72 years old. In general, I have aches and pains, something wrong every day. Don't know if that's Synthroid related or not. But I am very uncomfortable with all this weight, just doing everyday things."

3 / 10
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Frequently asked questions

  • davet...
  • Taken for 2 to 5 years
  • September 6, 2017

For Hashimoto's disease "Synthroid is only one of the four hormones produced by the thyroid. So it produces about the expected mediocre result. For me it was worse than mediocre, it was horrible, leaving me essentially bed-ridden for almost 3 years. This company has a bad record, and pressure is put on Docs to use this stuff exclusively. Why aren't we offered other options at the start??"

3 / 10
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  • Lbjaz
  • Taken for 5 to 10 years
  • January 13, 2018

For Hypothyroidism, After Thyroid Removal "I'm taking Synthroid - its a horrible drug. I'm losing all my hair, headaches, insomnia, depression, fatigue, brain fog, etc.. This drug sucks I have no idea why doctors keep pushing this drug. I have a new insurance and Doctor hopefully I can start taking Armour If not I have no idea what's to come."

1 / 10
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Are you taking this medicine?

  • Marbunk
  • June 17, 2021

For Underactive Thyroid "I have taken Synthroid (branded) since 2005 (dose .075) with no issues or side effects, have kept annual notes on TSH t3 t4 test results since that date. Recently, my TSH dropped to .25 with t3 and t4 in normal range. Doc switched me to .50 from .075 because my TSH was low. The side effects were absolutely awful for 5 weeks with the worst being muscular pain throughout my whole body afraid my legs would give out. I stopped taking after 5 weeks for 2 days while waiting to see Doc to see whats happening. Within 1.5 days, the symptoms relieved without any pain medication. I believe there is some change to the drug and have contacted Abbvie (waiting for an answer) to see if the fillers (which are numerous) have been changed from 1 dosage to another. If you are having any side effects, you must call them and report it, especially if they are long term or severe as mine were. I am back on .075 with no issues...... something is wrong here. Will keep posted."

1 / 10
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  • Anony...
  • Taken for 1 to 6 months
  • July 19, 2019

For Hashimoto's disease "Was diagnosed with hashimotos about 2 months ago. I would wake up feeling very fatigued and I would have to take a power nap at work before I could drive home. I had seen the endocrinologist and he put me on 50 mg of Synthroid once a day. After about two weeks I felt great, l was back to my normal self minus the weight I gained (10 lbs in 2 weeks). Now all the sudden I woke up this past Monday with a migraine and no appetite. Today is Friday, still battling the migraine and have lost 7lbs. Every time I think of food I want to vomit. Had labs done and everything came back normal. Body feels very hot and a lot of sweating. Doc lowered me to 25 mg on Wednesday but still no changes in headache or appetite."

1 / 10
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More FAQ

  • Twisted...
  • May 29, 2011

For Hypothyroidism, After Thyroid Removal "I am a 38 year old female. I had my thyroid removed about 7 months ago because I had thyroid cancer. I have been on Synthroid for about five months. My endocrinologist has a great deal of experience, so we found my correct dose after only two tries. Once I was at my correct replacement dose, I felt great. I feel just well, if not better, than I did before I was diagnosed. I am counting off a point only because Synthroid (though this is the case with all brands of levothyroxine) is a nuisance to take everyday, and it requires some planning if one must (as I do) take calcium and iron supplements every day as well."

9 / 10
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  • Anonymous
  • August 21, 2012

For Hashimoto's disease "I have been on Synthroid now for 4 years. I wasn't able to take the generic Levothyroxine because it caused me high blood pressure. I was shocked to find out I had Thyroid disease. My dosage continues to go up I'm on 125mcg now, and just had my TSH checked and its again on the low end (which I can tell because of fatigue, weight gain, hair loss). I demand my thyroid to be tested every 4 months. When its in the middle of "Normal" range is the only time I feel good!"

10 / 10
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  • ThisG...
  • Taken for less than 1 month
  • April 25, 2017

For Underactive Thyroid "After seeing my ob for some problems with menstruation, I was sent for about 10 different blood test to check my hormone levels. Let's just say that we found the source of my problem and I was referred to an endocrinologist. She wanted to repeat my TSH level cause she said that being at 3.65 was a little high for someone my age. So I went back within 4 weeks to get retested and my TSH was 10.36 and I was feeling it. I was so tired I could barely get out of bed. My headaches were out of control and I gained about 10 lbs in a months time. I just started 75mg Synthroid a few days ago so I'm feeling optimistic. I feel once we get my pituitary adenoma, thyroid and my vitamin D under control I'll be so much better. ADVICE: listen to your body."

6 / 10
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  • Anonymous
  • Taken for less than 1 month
  • July 12, 2012

For Hashimoto's disease "Suffering for years from all symptoms of hypothryroidism and mother has Hashimoto's. Finally doctor did thyroid tests. My thyroid peroxidase asb level was 170 but Free T4 and T3 within normal range. Doc prescribed 100mg Synthroid to start. Wow! In three days I could tell a difference. I rated Synthroid 8 of 10. Time will tell if I have side effects, but for the time being after one week on Synthroid I feel like a new person."

8 / 10
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  • Anonymous
  • October 2, 2009

For Hashimoto's disease "Synthroid has changed my life -- from 16 hours/day in bed to being an active medical school student. The only side effect I have experienced is dry eye in the mornings, but that is fine with the use of artificial tears. I used Synthroid for my Hashimoto's and now continue to use it post-thyroidectomy. I only use the Synthroid name brand because generics could be made at different labs and will not be exactly the same every month. Talk to your doctor about using generics. My doctors only prescribe the name brand for me because it is important to have constant thyroid hormone levels."

10 / 10
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  • Ayapl...
  • December 6, 2017

For Underactive Thyroid "I used Synthroid (25, 50 or 75 for over more than 10 years, but had to use the original, not the generic because generic does not work in some people. I've not been operated, but for over 2 years I've been using NatureThroid (32.5) instead which was recommended by my ND and have to say that all my side effects that Synthroid caused, had gone. I almost lost all my hair and had terrible heart beats, headaches, joint pains, etc. I do not have hashimoto, and really don't know if it works for people with this condition, but I tried NatureThroid and I am very happy with the results."

1 / 10
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  • Gizelle
  • March 24, 2016

For Hypothyroidism, After Thyroid Removal "I have been on Synthroid 15 years now, two years ago my insurance company would not cover Synthroid any more so they sent me the generic. I broke out in a rash and felt awful. My Dr wrote for synthroid only. I am paying 288.00 a year now out of pocket instead of 16.00. I am not sure what happen but my belly has been bloated every since and I have gained 40 pounds! My new Dr of Internal Medicine does not seem to care and says it's my age bla bla bla. I told her I wanted to be tested for hashimoto and she said there was no doubt in her mind that I have it. My thyroid is totally not working and i am taking 125 Mcg a day. I am not sure what else I can do as she does not seem to want to help. Me gaining 40 pounds is not acceptable."

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  • Marykp
  • September 23, 2015

For Hypothyroidism, After Thyroid Removal "My thyroid was removed in September 1993 due to Papillary Carcinoma. After removal and treatment, I was put on generic synthroid and could not get my levels regulated. After a time, I was put on brand name Synthroid and levelled out. I am unable to take the generic."

9 / 10
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  • Anonymous
  • January 25, 2011

For Hypothyroidism, After Thyroid Removal "I had my thyroid removed in February 2009 and was on Levothroid until about 2 months ago. It did nothing to help. I switched to Synthroid and it seems to work better, but I still am feeling depressed, difficulty concentrating and have trouble remembering things, like any new information given to me. I just haven't felt like myself since the surgery."

8 / 10
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  • Anonymous
  • June 24, 2010

For Hashimoto's disease "I was on this medicine for about 6 months and in that time I felt worse than when I wasn't taking it. It took the migraines away but I still had muscle aches, fatigue, hair loss, dry skin, brittle nails and more. The huge symptom I had on this medicine that bothered me is the depression. I felt dread and doom everyday. I couldn't take it anymore, so I stopped taking it, then I went to a different doctor that prescribed me Armour."

1 / 10
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  • kitcat
  • Taken for 5 to 10 years
  • October 4, 2017

For Underactive Thyroid "I was put on synthroid 1 year after telling my Endocrinologist (he was taking care of my type 1 diabetes) that I think I have low thyroid (it runs in my family). After a year he finally tested my TSH which was high and put me on Synthroid. My TSH came back fine but I told him my hair was still thinning, my nails were still brittle, my stomach was still swollen & I got every bug that was within 100 miles. I also developed total exhaustion and only left the house for doctor appointments. I went from 103lbs. to 130lbs. He put me on a higher dose and switched me to Levothyroxine (generic for synthroid) which caused rash & itching on face, then on rest of body, felt like a ball in my throat. Changing doctors now."

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  • Anonymous
  • October 4, 2009

For Underactive Thyroid "I've been taking Synthroid for a few years and has really helped. My dose has gone up several times. I can really tell a change in how I feel now, then before I was taking it. Tried the generic and it actually made me feel worse so I am taking the name brand only."

9 / 10
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  • lilcal
  • Taken for 1 to 6 months
  • May 19, 2015

For Underactive Thyroid "I been taking .025 MG everyday for two months.... I was not sure why I was taking it... I know I had a super low sex drive n now have a high sex drive whereas I have to relieve my self two to three times a day... I get very horny for no reason n notice my sperm is more thicker n I'm producing a lot more now...."

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  • Michele...
  • April 11, 2015

For Hashimoto's disease "My hashimotos with benign nodule was found after losing my twins to early delivery. Endo believes this was a missed factor in my loss. My TSH was over 4. Started on levothyroxine 100 mcg was great for 2 months but by the third month my blood sugars dropped, heart was racing (palpitations ), body itching like the burn you feel after a workout, my hair was falling out, severe anxiety and I was losing 2 lbs every few days (that part I didn't mind). I was insistent to check my TSH and it was 0.27 adjusted down to 88 mcg with an extra half tab once a week. My TSH is now 2.2 but I feel the depression and fatigue. Adjusting back up to 100 since it's been 3 years. At least now I know what to watch for. I no longer experience PCOS OR DM 2."

10 / 10
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  • Rocke...
  • May 29, 2010

For Underactive Thyroid "I was born with a thyroid condition. I am 23 year old female. I did the other brand for a while, and made me tired, sad, and just made me feel hopeless. I am on Synthroid 88mcg and although I sometimes feel sad, my weight is maintained, I'm able to work, and play with my 1 year old daughter, who thank God is healthy. Finding the right dosage is so important and is a trial and error. If everything is good and you only have one symptom like sadness...get a hobby, again a close friend is so important and always take your pill!"

9 / 10
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  • Willm...
  • Taken for 6 months to 1 year
  • July 20, 2015

For Hypothyroidism, After Thyroid Removal "Due to variances in generic medications I kept experiencing thyroid fog until my doctor changed me to synthroid. My stats immediately stabilize and it has worked well. I found I must take it as prescribed and at the same time daily to avoid the fog."

9 / 10
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  • tmir
  • April 9, 2015

For Hypothyroidism, After Thyroid Removal "I had a goiter in my teens that was treated with radioactive iodine, I've been on synthroid for almost ten years, having trouble finding the right dose, I was on 125mcg for a few years but my TSH jumped around a lot, last time I checked it was around 30, so not good, I decided to try 150mcg at first I had a bit of insomnia but otherwise I felt great, going to find out on Saturday if it's been working as good as I thought, I ran out 3 days ago... and I've already gained a bit of weight (looks like I'm bloated) and woke up this morning depressed, oh well I get more on Saturday"

10 / 10
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  • Batty
  • January 3, 2018

For Underactive Thyroid "Thyroidectomy after cancer diagnosis and so far I've had not had great luck with synthyroid. Currently I'm on 112 mcg and it makes me feel like I have a itchy sunburn and the weight gain is insane I feel water logged in my legs most of the time and too many mental glitches. I dislike this drug it's has to many fillers that cause other issues. If you have a known allergies avoid synthyroid until they can create an allergy free version."

7 / 10
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32 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.