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Synthroid User Reviews & Ratings (Page 3)

Synthroid has an average rating of 6.1 out of 10 from a total of 189 reviews on Drugs.com. 51% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Synthroid

  • Dore
  • Taken for 5 to 10 years
  • September 8, 2019

For Hashimoto's disease "So sorry some of you are having this experience with Synthroid. I have been on this medication for 8 years now. When I started out with it, I had many of the same symptoms of all of you for about nine months. During that time I went thru 5 medication adjustments. Started out at 25 mcg , then ended up at 100mcg. Then went to taking the 100 mcg 5 times a week and cutting the pill in half two days. What worked for me is the following: -Take exactly the same time every morning -Do not eat or drink anything within the hour after that -Some medications and supplements interfere with the absorption of it. Take them 4 to 6 hours before or after. This is important because Synthroid is a narrow therapeutic dosing drug. In other words, if your dose isn't just right, you will experience all the negative side effects of both hypo and drug side effects. - If your dr isn't willing to adjust the dose for you like my dr has, find another dr."

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  • rick
  • August 6, 2020

For Hypothyroidism, After Thyroid Removal "Many doctors have begun to realize that many people are allergic to the ten or more additives in Synthroid. I had papillary thyroid cancer over 30 years ago. I had surgery and I have been sick for over 30 years. The brain fog was terrible. I have fired more than 20 doctors over this time. They always said, "Your lab report says your levels are fine". On my second visit to a holistic doctor, she changed me to Tirosint, which has no additives. Tirosint is relatively new and in produced in Europe. TRY TIROSINT. Please….You will not be sorry."

1 / 10
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  • Kat_PK
  • Taken for 1 to 6 months
  • September 15, 2016

For Underactive Thyroid "I was taking Levothyroxin 50mcg for the past 3 months. My initial tsh was 13 when I started Levo; within 2 months my tsh dropped to 2.5. Although my levels were normal, I continued to have some fatigue, sleepy upon waking, night sweats, facial flushing, anxiety, and horrible brain fog. I decided to try my sample of Synthroid 50mcg and within a week, the brain fog, night sweats and sleepiness were gone! I wake up with the most energy I have ever had! I am still experiencing some anxiety and facial flushing which we are monitoring but overall Synthroid is working for me! I am 32 y o and 9 months post partum. I also take my dose at nights, hours after dinner"

8 / 10
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Frequently asked questions

  • Dennise
  • Taken for 1 to 6 months
  • October 16, 2017

For Underactive Thyroid "My doctor prescribed Levothyroxine for low thyroid and I had been feeling so tired and wiped out. Levothyroxine did help improve my numbers (TSH of 7.5 dropped to 4.5) but I felt awful on it. Everything hurt and I was so exhausted. After 3 months on Levothryoxine, I asked to try the brand name Synthroid. What a difference!!! It improved my numbers even more (same dose, TSH decreased to 1.75) and not only that, I felt better. I had energy. My experience is night and day. I know generics are supposed to be equivalent but I can tell you there is a difference. Synthroid brand works so much better than Levothyroxine. Recommended."

10 / 10
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  • Anonymous
  • August 16, 2011

For Underactive Thyroid "The only confirmation I have that it works is my blood work. I feel no better or worse on Synthroid. It is very annoying to take. You have to take it in the morning, on an empty stomach, no food for an hour. And for some, no calcium for two hours. Tell me how do you eat breakfast with this medicine!? It does work though, so I gave it an 8."

8 / 10
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Are you taking this medicine?

  • AmyBill
  • August 13, 2016

For Underactive Thyroid "Diagnosed with Graves disease, my thyroid was radiated and destroyed. Put on synthyroid, took a while to get dosage right, but I have been on it for 8 years now and without it I would want to die. I take 100 mcg a day and I set my phone alarm to go off same time every day so I won't forget it."

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  • SaltW...
  • March 26, 2015

For Hypothyroidism, After Thyroid Removal "In a nutshell I had my thyroid removed ten years ago. I had a lot of horrible symptoms that I can only describe myself as feeling like a 100 year severely arthritic woman. My lab results seemed to always came out within range no matter what dosage I was on. I even called the synthroid company to discuss the various doses and learned the only difference between the doses I was trying besides the amount of thyroid hormone as the food coloring. In a quick internet search I learned my symptoms might be related to the food dyes. My endo rewrote my prescription using no dye tablets. With one week I had no pain. I take two 50mcg daily and on Monday and Thursday I add a half tablet. Life is good!"

9 / 10
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More FAQ

  • Teddy...
  • July 31, 2016

For Underactive Thyroid "I feel awful! I have been on this drug for 6 weeks! I have so many side effects 1. Very tired ( no Energy) 2. Nausea 3. Headache 4. Can't sleep ( even if I take a sleeping) 5 Always feel Hot 6. Sweating 7. Clammy skin (have to the fan on on all the time) I live in Canada so it not that hot. Never felt so sick."

1 / 10
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  • Art
  • Taken for 10 years or more
  • August 21, 2018

For Underactive Thyroid "I have been on Synthroid for 12 years and I have had no side effects. I only have good things to say about this drug. However, when you start blood tests are essential to determine the right dosage. You must take on an empty stomach and no food for about an hour. Also, you need to keep the Synthroid level constant in your blood system. If you skip a day or two It is like you have to start over to get back to the dosage you were prescribed. This drug works. Use it as your Dr. tells you to and have blood tests on a regular basis."

9 / 10
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  • Anonymous
  • September 27, 2009

For Underactive Thyroid "I was born without a thyroid and I've been taking Synthroid every night. I'm only 13. I have to tell you this is the best thing ever. If I didn't have this medication I would be barely alive. I wouldn't be this tall either (5'7). This medicine is my life-line. "

10 / 10
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  • plinv...
  • October 25, 2009

For Underactive Thyroid "I have taken Synthroid for 23 years. The first 3 years I did okay on it but over the past 20 I started to feel losey. I'm tired all the time and very irritable. I've taken from .050 MG to .125. I still feel bad. It's been adjust at least 30 to 35 times through the course of 23 years. I feel totally helpless and hopeless. My doctor will not change my thyroid medication."

2 / 10
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  • Anonymous
  • February 20, 2012

For Underactive Thyroid "Have been taking thyroid medicines 10 years. I found that the generic version is not adsorbed as well as the synthroid. Went back to brand name a few days ago and am no long tired and my period finally stopped after 3 continuous Weeks. 10 on scale for sure!"

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  • CatB
  • Taken for 10 years or more
  • November 27, 2020

For Underactive Thyroid "I have been on Synthroid since 1993. Prior to starting it, I couldn't lose weight no matter what I did. It was and is the help I needed. After being on Synthroid for about a decade, my insurance requested I switch to a generic. After a couple of months, my TSH levels were no longer balanced and my dose was increased. After nearly a year of no control, no matter what dose I was on, my levels and symptoms wouldn't stabilize. My doctor and I realized the change happened when I was switched to the generic. It took several months back on the Synthroid before I was stable again. No more generics for me, now it's my wallet getting lighter because of how expensive it is. But at least my levels are stable."

10 / 10
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  • mizzg...
  • December 30, 2016

For Hypothyroidism, After Thyroid Removal "I ended up with an emergency complete thyroidectomy after an ultrasound revealed the tumors ((2 in each lobe of my thyroid) had grown and were the culprit to me having to turn my head to the left to swallow food or to even drink liquid. After years of taking levithyroxine I was put onto the brand name Synthroid. At worst, my levels were 86.4. Yes, you read that correctly. My my hair falls out in clumps, tired, exhausted, body aches and joint pain, chronic fatigue, etc. now my routine is to take my synthroid at bedtime with vitamin c. I wake up fine, I'm down from 325 to 181 and I feel great! Please remember your thyroid takes weeks/months to change, you won't notice anything three days to a month into taking this"

10 / 10
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  • l2b
  • Taken for 1 to 6 months
  • April 28, 2015

For Hypothyroidism, After Thyroid Removal "Due to thyroidectomy I am hypo thyroid .While on synthroid I felt awful. High anxiety, quick to anger. Definitely did not like this drug. I like levoxly and naturethroid. Doing better. Keep trying other meds if you feel awful."

2 / 10
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  • Anonymous
  • July 3, 2008

For Underactive Thyroid "I have been taking Synthroid for about eight years now. I have tried the generic Levoxothyrine and it makes shaky all over even at the same dosage. My history has been going from hyperthyroid, caused by thyroiditis, to hypothyroid afterwards. I take my dose religiously every morning 1 hour before breakfast. Even in light of this I seem to have great fluctuations in my levels. I assume this is more a physiological problem than that of the medication. When we get it leveled out, I feel well."

8 / 10
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  • Anonymous
  • December 10, 2011

For Hashimoto's disease "If you are taking Synthroid and you are still depressed, overweight or losing hair (all symptoms of hypothyroidism, which this drug treats) then your dose is still not high enough. If your doctor tells you that you are "within the normal range, "switch doctors - if you are still having symptoms then your dose should be higher. I have been on this medication for several years now and as long as I'm on the right dose, I feel fine. I know I need an adjustment when I start to get tired and depressed. Those are the two most obvious symptoms for me (as well as hair loss). I have used low-carb diets effectively (New Atkins for a New You is good - has a section for vegetarians) to lose the weight I had gained when my thyroid became inactive."

10 / 10
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  • MissB...
  • Taken for 2 to 5 years
  • October 1, 2018

For Hashimoto's disease "I've been taking generic (levothyroxine) for 2.5 years. I took for a little while about 4 years but I didn't keep up with my health as I should have. My TSH was 58.8 and I started on 50 mcg. After seeing my GP and now an Endocrinologist, I am now up to 150 mcg and the last TSH was .99 I have had no side effects from either Synthroid or the generic. The medicine does what it's supposed to do. My hair grew back, the fog lifted, got my energy back, severe muscle pain went away, joints no longer hurt and my cholesterol went down from 280 to 200. I take it in the morning but don't follow any rules. The endo just said to take it. I usually take it with my Vitamin D, prescription pepcid, and Vitamin C. I take it with coffee or milk. The endo said it really didn't matter, just take it because not taking it is not an option."

10 / 10
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  • KFSI
  • April 13, 2011

For Underactive Thyroid "I have been on Synthroid for over 8 years and have actually gained weight. I have a very healthy lifestyle (exercise for one hour 5 days a week, and eat healthy), but nothing has been working. My endocrinologist consistently increases my prescription and nothing changes. Next time I see her I am going to get on Armour. "

2 / 10
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  • jrb
  • Taken for less than 1 month
  • February 7, 2020

For Underactive Thyroid "I had a partial thyroidectomy in 2007. I've been on generic Levo 88mcg for about 10 years now. Maybe it would be different had I been started on Synthroid from the get go but I've tried Synthroid two times, once at 75mcg and this week at 88mcg and the results were the same. Within three days I had muscle weakness, muscle spasms, more pain in neck and extreme fatigue. Regulation mandates 95-105 % of the active ingredient be present. I've taken Unithroid 88mcg and I never had the extreme symptoms like with Synthroid. I steer clear of this med because I can't afford to miss another week of pay fiddling around with it. Generic and Unithroid aren't perfect but at least I can function."

1 / 10
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  • Mizz...
  • October 27, 2014

For Underactive Thyroid "Had partial thyroid removal with benign tumor 30+ years ago, was OK until about 2 years ago and routine bloodwork showed low thyroid. After 2 years being OK on the medication suddenly the thyroid levels are dropping again, hair falling out, skin is breaking out in itchy red welts, gaining weight, so Dr upped the dosage. A couple weeks on higher dose I feel like I am "wired" in high gear, can't sit still, talking to myself going in circles, and my hot flashes have really really ramped up big time. Dr. says to give it at least 60 preferably 90 days to adjust, not sure I can hold out that long before stopping it. Hoping there is a better solution out there someplace."

7 / 10
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  • Anonymous
  • December 22, 2011

For Hypothyroidism, After Thyroid Removal "I do not feel too much of a difference from before I had my thyroid removed. I do understand how so many people have such a wide variety of symptoms. I can say though that my weight is lower than ever, even my teenage years. My hair does seem to be thinner and cannot tolerate cold very much but that is pretty much it."

10 / 10
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  • Hypos...
  • Taken for 5 to 10 years
  • November 7, 2013

For Hashimoto's disease "6+ years on Synthroid, and this is what I have to show for it..Used to be a size 12 now a 28, no periods, pain all over, Hypo symptoms still, mental and mood symptoms ( anxiety, depression, mood swings) My Growth Hormone is only 40 and my FSH is 78. I can't have children. Finally switched to Cytomel, it broke me out, and still had same symptoms as above. My level was over 20 last they checked. Just got a RX for Armour, hoping I finally get my life back"

1 / 10
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  • CMIRE
  • March 6, 2012

For Underactive Thyroid "I've been taking synthroid for about 3 years. I had to have radiation on my thyroids because they couldn't control levels. It just would go real low than extremely high. I'm on a 300 mg taking mon through to sat. I'm feeling better but it takes a long time before they find the right dosage."

9 / 10
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  • Alex
  • June 14, 2019

For Hypothyroidism, After Thyroid Removal "I have been on a roller coaster ride for the last 3 to 4 years. Every time my levels are checked then come back off. I had been on levoxyl 100 for years and don’t recall having any issues. Due to health insurance change I was switched to levothyroxine 100 and problems started happening. On levothyroxine 100 my levels would be out of whack and the doctors switched the dosage to 112 and I thought I was dying. Within a couple of days my joints, back, neck and feet would ache. Started getting palpitations felt like I was having a heart attack. Ended up in ER because of fast heart rate and heaviness and numbness of the left side of my body. Doctors thought I was having a stroke. I was switched to Syntheroid 100. 6 days on it. I have such bad pain through out my body and joints. My legs feel as if they are swelling. I have tried armour and immediately developed double violin and dizziness. I have stomach issues and gluten sensitivity."

2 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.