Psoriasis
Animation of the skin layers and normal function of skin cells showing the immune response and what goes wrong in the skin cells causing psoriasis.
Video transcript
Psoriasis results from a problem with a type of white blood cell in the immune system called a T cell. T cells normally detect and fight off foreign substances. In psoriasis, T cells attack healthy skin cells and trigger an immune response.
Blood vessels in the skin get larger. Other white blood cells enter the epidermis. The T cells release messenger chemicals called cytokines, which tell the keratinocytes to reproduce and mature much faster than normal.
New skin cells form and move to the surface too quickly. They build up as the thick, scaly patches on the skin's surface that characterize psoriasis.
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