advantus (imidacloprid) soft chew
This treatment applies to the following species:advantus is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.
Active Ingredients
advantus contains 7.5 mg or 37.5 mg of imidacloprid.
Use: advantus kills adult fleas and is indicated for the treatment of flea infestations on dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.
Warnings
Not for human use. Keep this and all drugs out of reach of children.Keep advantus in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.
Side Effects
Side effects seen with this drug include vomiting, decreased appetite, decreased energy, soft stools and difficulty walking.Directions: You should weigh your dog before giving this medication to make sure you are using the right size for your dog. Do not give to puppies younger than 10 weeks of age or to dogs weighing less than 4 pounds. Do not give more than one tablet a day.
Use the table to find the right dose for your dog:
Dosing Table |
||
Body Weight |
Dose* |
Soft Chew Strength |
4-22 lbs |
One Soft Chew |
7.5 mg imidacloprid |
23-110 lbs |
One Soft Chew |
37.5 mg imidacloprid |
*If your dog becomes re-infested, you can safely repeat treatment as often as once a day.
To give advantus, place the soft chew directly in your dog’s mouth or allow your dog to take the soft chew from your hand. Watch closely to ensure your dog swallows the soft chew.
A single dose kills adult fleas on your dog. Because advantus does not have an effect on fleas in the environment, your dog may become re-infested with fleas. If your dog becomes re-infested, you can safely repeat treatment as often as once a day. Contact your veterinarian if you have any questions about flea infestations on your dog.
Treat all pets in your household with a flea protection product. advantus should only be given to dogs.
Questions/Comments? For product questions or to report side effects, call Elanco at 888-545-5973. For additional information about reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or http://www.fda.gov/reportanimalae
Other Information:
● Contact your veterinarian if your dog ingests more than the recommended dose of advantus.
● advantus has not been tested in pregnant or nursing dogs.
● advantus starts to kill fleas within 1 hour. A study demonstrated that advantus achieves greater than 96% effectiveness against adult fleas within 4 hours.
● advantus may be used together with other products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos.
● advantus does not protect against ticks or mosquitoes.
Flea Infestations on Dogs: Treatment of flea infestations is important to your dog’s health. Fleas in your dog’s environment can re-infest your dog. Therefore, you may need to treat with advantus more than one time. The following diagram illustrates the flea’s life cycle and where advantus works:

Fleas reproduce rapidly. A single female flea may produce up to 2,000 eggs over her lifetime. Eggs hatch and may grow into adults in only three weeks. Adult female fleas feed by ingesting blood from your dog and lay eggs that drop off from your dog’s coat. Within days, larvae hatch from these eggs and live undetected in your dog’s surroundings, such as in the carpet and bedding. Fleas can emerge to re-infest your pet, continuing the life cycle. When these new fleas are seen on your dog, treat with advantus.
If you have any questions about flea treatment or medical problems associated with flea infestations, consult your veterinarian.
Storage Information: Store at temperatures between 68° and 77°F (20°-25°C).
How Supplied
advantus is available in two strengths: 7.5 mg or 37.5 mg imidacloprid. Both strengths are packaged in 7 count bottles containing 7 flavored soft chews or 30 count bottles containing 30 flavored soft chews.Approved by FDA under NADA # 141-435
Manufactured for:
Elanco US Inc., Greenfield, IN 46140 U.S.A.
90207038_PA600215X
Revised: January 2022
Made in Spain.
advantus, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.
© 2022 Elanco or its affiliates
CPN: 1131112.1
2500 INNOVATION WAY, GREENFIELD, IN, 46140
Customer Service: | 317-276-1262 | |
Technical Service: | 800-428-4441 | |
Website: | www.elanco.us | |
Email: | elanco@elanco.com |
![]() |
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details. |
Copyright © 2025 Animalytix LLC. Updated: 2025-03-02