Vicks NyQuil Cold & Flu Nighttime Relief Side Effects

Generic name: acetaminophen / dextromethorphan / doxylamine

Medically reviewed by Drugs.com. Last updated on Apr 21, 2024.

Note: This document provides detailed information about Vicks NyQuil Cold & Flu Nighttime Relief Side Effects associated with acetaminophen / dextromethorphan / doxylamine. Some dosage forms listed on this page may not apply specifically to the brand name Vicks NyQuil Cold & Flu Nighttime Relief.

Applies to acetaminophen / dextromethorphan / doxylamine: oral capsule, oral liquid.

Important warnings This medicine can cause some serious health issues

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days.

A dangerous drug interaction could occur.

MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).

In rare cases, acetaminophen may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never again take any medicine that contains acetaminophen.

Stop using the medicine and call your doctor at once if you have:

• severe headache, seizure (convulsions);

• fast, pounding, or uneven heartbeats;

• confusion, hallucinations, severe dizziness or drowsiness, slow or shallow breathing;

• tremor, restless muscle movements;

• little or no urinating;

• flu symptoms, easy bruising, unusual bleeding, pale skin, weakness, feeling light-headed; or

• nausea, pain in your upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

• headache, sleep problems (insomnia);

• upset stomach, diarrhea or constipation;

• dry eyes, blurred vision, dry mouth or nose;

• mild dizziness or drowsiness, trouble concentrating;

• feeling restless or excited (especially in children); or

• mild skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Further information

Vicks NyQuil Cold & Flu Nighttime Relief side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer