VESIcare LS Side Effects

Generic name: solifenacin

Medically reviewed by Drugs.com. Last updated on Oct 31, 2023.

Note: This document provides detailed information about VESIcare LS Side Effects associated with solifenacin. Some dosage forms listed on this page may not apply specifically to the brand name VESIcare LS.

Applies to solifenacin: oral suspension, oral tablet.

Serious side effects of VESIcare LS

Along with its needed effects, solifenacin (the active ingredient contained in VESIcare LS) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking solifenacin:

More common side effects

• constipation
• stomach pain

Less common side effects

• bladder pain
• bloody or cloudy urine
• blurred vision
• chills
• decrease in the frequency of urination
• decrease in urine volume
• difficult, burning, or painful urination
• dizziness
• dry eyes
• fever
• frequent urge to urinate
• headache
• lower back or side pain
• nervousness
• pounding in the ears
• slow or fast heartbeat
• swelling of the lower legs
• unusual tiredness or weakness

Incidence not known

• bloating or swelling of the face, arms, hands, lower legs, or feet
• body aches or pain
• chest pain or discomfort
• confusion
• cough
• decreased or increased sweating
• diarrhea
• discouragement
• dry skin
• fainting
• feeling sad or empty
• general feeling of discomfort or illness
• hives or welts, itching, skin rash
• hoarseness
• irregular heartbeat recurrent
• irritability
• joint pain
• lack of appetite
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• loss of interest or pleasure
• muscle aches and pains
• redness of the skin
• runny or stuffy nose
• seeing, hearing, or feeling things that are not there
• shivering
• sore throat
• tender, swollen glands in the neck
• tingling of the hands or feet
• trouble concentrating
• trouble with sleeping
• trouble with swallowing
• unusual weight gain or loss
• voice changes

Other side effects of VESIcare LS

Some side effects of solifenacin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• dry mouth

Less common side effects

• acid or sour stomach
• belching
• heartburn
• indigestion
• nausea
• stomach discomfort or upset
• vomiting

For healthcare professionals

Applies to solifenacin: oral suspension, oral tablet.

Gastrointestinal adverse events

• Very common (10% or more): Dry mouth (up to 28%), constipation (up to 13%)
• Common (1% to 10%): Nausea, dyspepsia, upper abdominal pain, vomiting
• Uncommon (0.1% to 1%): Gastroesophageal reflux disease, dry throat, flatulence, throat irritation, eructation, thirst
• Rare (less than 0.1%): Colonic obstruction, fecal impaction
• Postmarketing reports: Ileus^[Ref]

Respiratory

• Common (1% to 10%): Pharyngitis, cough, sinusitis, bronchitis
• Uncommon (0.1% to 1%): Nasal dryness
• Postmarketing reports: Dysphonia^[Ref]

Psychiatric

• Common (1% to 10%): Depression
• Postmarketing reports: Confusion, hallucinations, delirium, somnolence^[Ref]

Ocular

• Common (1% to 10%): Blurred vision, dry eyes
• Very rare (less than 0.01%): Glaucoma^[Ref]

Genitourinary

• Common (1% to 10%): Urinary tract infection, urinary retention
• Uncommon (0.1% to 1%): Cystitis, suprapubic pain, bladder pain, micturition urgency^[Ref]

Cardiovascular

• Common (1% to 10%): Lower limb edema, hypertension
• Uncommon (0.1% to 1%): Syncope, chest tightness, hot flushes
• Postmarketing reports: Peripheral edema, QT prolongation, Torsade de Pointes, atrial fibrillation, tachycardia, palpitations, atrial fibrillation^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Dry skin
• Rare (0.01% to 0.1%): Pruritus, rash
• Very rare (less than 0.01%): Erythema multiforme, urticaria, angioedema, exfoliative dermatitis^[Ref]

Immunologic

• Common (1% to 10%): Influenza^[Ref]

Metabolic

• Very rare (less than 0.01%): Decreased appetite, hyperkalemia^[Ref]

Hypersensitivity

• Very rare (less than 0.01%): Hypersensitivity reactions (including angioedema with airway obstruction, rash, pruritus, urticaria, and anaphylactic reaction)^[Ref]

Other

• Common (1% to 10%): Fatigue^[Ref]

Renal

• Very rare (less than 0.01%): Renal impairment^[Ref]

Hepatic

• Postmarketing reports: Abnormal liver function tests, AST (aspartate aminotransferase), ALT (alanine aminotransferase), GGT (gamma-glutamyl transferase)^[Ref]

Musculoskeletal

• Common (1% to 10%): Arthralgia, back pain
• Uncommon (0.1% to 1%): Neck pain
• Postmarketing reports: Muscular weakness^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, insomnia
• Uncommon (0.1% to 1%): Dysgeusia
• Rare (0.01% to 0.1%): Headache
• Postmarketing reports: Headache, tremors^[Ref]

Further information

VESIcare LS side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer