Vamorolone Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 10, 2024.

Applies to vamorolone: oral suspension.

Side effects include:

Most common adverse reactions (>10%): cushingoid features, psychiatric disorders, vomiting, increased weight, vitamin D deficiency.

For healthcare professionals

Applies to vamorolone: oral suspension.

General adverse events

The most common adverse reactions occurring in greater than 10% of treated patients included cushingoid features, psychiatric disorders, vomiting, increased weight, and vitamin D deficiency.^[Ref]

Cardiovascular

• Frequency not reported: Thromboembolic events, elevated blood pressure

Endocrine

• Very common (10% or more): Cushingoid features (up to 29%)
• Frequency not reported: Pheochromocytoma crisis, increased blood glucose, Cushing's syndrome (hypercortisolism), acute adrenal insufficiency (after abrupt withdrawal)

Gastrointestinal

• Very common (10% or more): Vomiting (up to 17%)
• Common (1% to 10%): Diarrhea
• Frequency not reported: Gastrointestinal perforation

Hematologic

• Frequency not reported: Increased lymphocyte and neutrophil counts

Hypersensitivity

• Frequency not reported: Anaphylaxis

Immunologic

• Frequency not reported: Reduced resistance to new infections

Metabolic

• Very common (10% or more): Increased weight (up to 11%), vitamin D deficiency (up to 11%)
• Common (1% to 10%): Increased appetite
• Frequency not reported: Increased excretion of potassium and calcium, salt and water retention

Musculoskeletal

• Frequency not reported: Avascular necrosis, decreased bone formation, increased bone resorption

Nervous system

• Common (1% to 10%): Headache

Ocular

• Frequency not reported: Posterior subcapsular cataracts

Oncologic

• Frequency not reported: Kaposi's sarcoma

Other

• Frequency not reported: Activation of latent amebiasis, exacerbation of systemic fungal infections, hepatitis B virus reactivation

Psychiatric

• Very common (10% or more): Psychiatric disorders (up to 21%)

Psychiatric disorders included abnormal behavior, aggression, agitation, anxiety, irritability, mood altered, sleep disorder, and stereotypy.

Respiratory

• Very common (10% or more): Cough (up to 10%)
• Common (1% to 10%): Rhinitis

Further information

Vamorolone side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer