Valstar Side Effects
Generic name: valrubicin
Medically reviewed by Drugs.com. Last updated on Aug 28, 2023.
Note: This document contains side effect information about valrubicin. Some dosage forms listed on this page may not apply to the brand name Valstar.
Applies to valrubicin: intravesical solution.
Serious side effects of Valstar
Along with its needed effects, valrubicin (the active ingredient contained in Valstar) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Other side effects of Valstar
Some side effects of valrubicin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Blood in urine
- loss of bladder control
- painful or difficult urination
- red color in urine
- strong urge to urinate
- unusually frequent urination
Less common
- Increased urination at night
- local burning sensation
Rare
- Frequent urge to defecate
- itching
- loss of sense of taste
For Healthcare Professionals
Applies to valrubicin: intravesical solution.
Local
Very common (10% or more): Any local bladder symptom (88%)
Common (1% to 10%): Procedure related local burning symptoms[Ref]
Local adverse reactions associated with valrubicin usually occurred during or shortly after instillate and resolve within one to seven days after the instillation is removed from the bladder.[Ref]
Genitourinary
Very common (10% or more): Urinary frequency (61%), urinary urgency (57%), dysuria (56%), bladder spasm (31%), hematuria (29%), bladder pain (28%), urinary incontinence (22%), urinary tract infection (15%), cystitis (15%)
Common (1% to 10%): Nocturia, urinary retention, microscopic hematuria, urethral pain, pelvic pain, gross hematuria
Frequency not reported: Poor urine flow, urethritis[Ref]
General
The most common side effects were local bladder symptoms, including urinary frequency, urinary urgency, and dysuria.[Ref]
Gastrointestinal
Common (1% to 10%): Abdominal pain, nausea, diarrhea, vomiting, flatulence
Frequency not reported: Tenesmus[Ref]
Nervous system
Common (1% to 10%): Headache, dizziness
Frequency not reported: Taste loss[Ref]
Dermatologic
Common (1% to 10%): Rash
Frequency not reported: Pruritus, local skin irritation[Ref]
Cardiovascular
Common (1% to 10%): Vasodilation[Ref]
Hematologic
Common (1% to 10%): Anemia[Ref]
Metabolic
Common (1% to 10%): Hyperglycemia, peripheral edema
Frequency not reported: Nonprotein nitrogen increased[Ref]
Musculoskeletal
Common (1% to 10%): Back pain, myalgia[Ref]
Respiratory
Common (1% to 10%): Pneumonia[Ref]
Other
Common (1% to 10%): Asthenia, malaise, chest pain, fever
More about Valstar (valrubicin)
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References
1. (2001) "Product Information. Valstar (valrubicin)." Medeva Pharmaceuticals
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.