Uplizna Side Effects

Generic name: inebilizumab

Medically reviewed by Drugs.com. Last updated on Jan 25, 2025.

Note: This document provides detailed information about Uplizna Side Effects associated with inebilizumab. Some dosage forms listed on this page may not apply specifically to the brand name Uplizna.

Applies to inebilizumab: intravenous solution.

Serious side effects of Uplizna

Along with its needed effects, inebilizumab (the active ingredient contained in Uplizna) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking inebilizumab:

More common side effects

• black, tarry stools
• bladder pain
• bloody or cloudy urine
• chills
• cough
• difficult, burning, or painful urination
• dizziness
• facial swelling
• fever
• frequent urge to urinate
• headache
• lower back or side pain
• muscle aches
• nausea
• pale skin
• skin rash
• sore throat
• stuffy or runny nose
• trouble breathing
• ulcers, sores, or white spots in the mouth
• unusual bleeding or bruising
• unusual tiredness or weakness
• vomiting

Other side effects of Uplizna

Some side effects of inebilizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• back or joint pain
• difficulty in moving
• muscle stiffness

Incidence not known

• pain, itching, burning, swelling, or redness at the injection site

For healthcare professionals

Applies to inebilizumab: intravenous solution.

General adverse events

The most commonly reported adverse events include infusion reaction, nasopharyngitis, urinary tract infection, arthralgia, back pain, and headache.

Hematologic

• Common (1% to 10%): Neutropenia
• Frequency not reported: Lymphocytopenia^[Ref]

Immunologic

• Common (1% to 10%): Anti-drug antibodies^[Ref]

Musculoskeletal

• Common (1% to 10%): Arthralgia , back pain^[Ref]

Genitourinary

• Very common (10% or more): Urinary tract infection (20%)

Respiratory

• Very common (10% or more): Nasopharyngitis (13%)
• Common (1% to 10%): Upper respiratory tract infection, influenza^[Ref]

Other

• Very common (10% or more): Infusion reaction (11.6%)^[Ref]

Nervous system

• Common (1% to 10%): Headache^[Ref]

Further information

Uplizna side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer