Tessalon Perles Side Effects

Generic name: benzonatate

Medically reviewed by Drugs.com. Last updated on Mar 5, 2025.

Note: This document provides detailed information about Tessalon Perles Side Effects associated with benzonatate. Some dosage forms listed on this page may not apply specifically to the brand name Tessalon Perles.

Applies to benzonatate: oral capsule, oral capsule liquid filled.

Serious side effects of Tessalon Perles

Along with its needed effects, benzonatate (the active ingredient contained in Tessalon Perles) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking benzonatate:

Rare side effects

• confusion
• difficult breathing
• difficulty with speaking
• seeing things that are not there
• shortness of breath
• tightness in the chest
• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur while taking benzonatate:

Symptoms of overdose

• change in consciousness
• convulsions (seizures)
• loss of consciousness
• no blood pressure or pulse
• restlessness
• shakiness in the legs, arms, hands, or feet
• stopping of the heart
• trembling or shaking of the hands or feet
• unconsciousness

Other side effects of Tessalon Perles

Some side effects of benzonatate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare side effects

• burning sensation in the eyes
• constipation
• dizziness (mild)
• drowsiness (mild)
• headache
• itching
• nausea or vomiting
• skin rash
• stuffy nose

For healthcare professionals

Applies to benzonatate: oral capsule.

General adverse events

The most serious side effects reported were bronchospasm, laryngospasm, and cardiovascular collapse.^[Ref]

Hypersensitivity

• Frequency not reported: Bronchospasm, laryngospasm, cardiovascular collapse, hypersensitivity^[Ref]

Nervous system

• Frequency not reported: Sedation, headache, dizziness, mental confusion, visual hallucinations.^[Ref]

Respiratory

• Frequency not reported: Nasal congestion, numbness of the chest^[Ref]

Gastrointestinal

• Frequency not reported: Constipation, nausea, GI upset^[Ref]

Dermatologic

• Frequency not reported: Pruritus, skin eruptions^[Ref]

Ocular

• Frequency not reported: Sensation of burning in the eyes^[Ref]

Other

• Frequency not reported: Vague "chilly" sensation^[Ref]

Frequently asked questions

• Can benzonatate be used for a sore throat?

Further information

Tessalon Perles side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer