Polymyxin B/trimethoprim Ophthalmic Side Effects
Medically reviewed by Drugs.com. Last updated on Mar 13, 2025.
Applies to polymyxin b/trimethoprim ophthalmic: ophthalmic solution.
Serious side effects
Along with its needed effects, polymyxin b/trimethoprim ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking polymyxin b/trimethoprim ophthalmic:
More common side effects
- increased redness, burning, stinging, or itching of the eye
Incidence not known
- blurred vision
- change in color vision
- difficulty seeing at night
- increased sensitivity of the eyes to sunlight
- increased tearing
- rash around the eye
- swelling of the eyelid
For healthcare professionals
Applies to polymyxin b/trimethoprim ophthalmic: ophthalmic solution.
Ocular adverse events
Ocular side effects are the most common, and include local irritation, increased redness, burning, stinging, and/or itching. This may occur on instillation, within 48 hours, or at any time with extended use.[Ref]
Hypersensitivity
Hypersensitivity reactions have included lid edema, itching, increased redness, tearing, and/or circumocular rash.[Ref]
Dermatologic
Dermatologic side effects associated with oral trimethoprim have included photosensitivity.[Ref]
References
1. (2022) "Product Information. Polytrim (polymyxin B-trimethoprim ophthalmic)." Allergan Inc
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Further information
Polymyxin b/trimethoprim ophthalmic side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.