Permethrin Topical Side Effects
Medically reviewed by Drugs.com. Last updated on Mar 3, 2025.
Applies to permethrin topical: topical cream, topical liquid, topical lotion.
Common side effects of permethrin topical
Some side effects of permethrin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common or rare side effects
Serious side effects of permethrin topical
Along with its needed effects, permethrin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
For healthcare professionals
Applies to permethrin topical: topical cream, topical kit, topical lotion, topical solution, topical spray.
General adverse events
General side effects have included fever.[Ref]
Dermatologic
Dermatological side effects have included pruritus (7%), erythema (1% to 2%), and rash (1% to 2%).[Ref]
Nervous system
Nervous system side effects have included numbness and tingling (1% to 2%). Headache and dizziness have also been reported. Rare occurrences of seizure have been reported; however, an association with the use of permethrin topical has not been confirmed.[Ref]
Gastrointestinal
Gastrointestinal side effects have included abdominal pain, diarrhea, and nausea and/or vomiting.[Ref]
Local
Local side effects have included mild and transient burning and stinging usually associated with the severity of infestation.[Ref]
References
1. (2006) "Product Information. Elimite (permethrin topical)." Allergan Inc
Frequently asked questions
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Further information
Permethrin topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.