Nicotinamide Side Effects
Applies to nicotinamide: compounding powder, oral capsule, oral capsule extended release, oral liquid, oral tablet, oral tablet extended release.
Cardiovascular adverse events
- Very common (10% or more): Flushing (i.e., warmth, redness, itching, and/or tingling) (up to 88%)
- Frequency not reported: Tachycardia, palpitations, atrial fibrillation, other cardiac arrhythmias, syncope, hypotension, postural hypotension[Ref]
Dermatologic
- Common (1% to 10%): Rash, pruritus
- Frequency not reported: Sweating, skin burning sensation, maculopapular rash, dry skin
- Postmarketing reports: Skin discoloration[Ref]
Gastrointestinal
- Very common (10% or more): Diarrhea (up to 14%), nausea (up to 11%)
- Common (1% to 10%): Vomiting
- Frequency not reported: Peptic ulcers, eructation, flatulence[Ref]
Hematologic
- Postmarketing reports: Slight reductions in platelet counts, prothrombin time prolonged[Ref]
Hypersensitivity
- Postmarketing reports: Hypersensitivity reactions (e.g., anaphylaxis, angioedema, urticaria, flushing, dyspnea, tongue edema, larynx edema, face edema, peripheral edema, laryngismus, vesiculobullous rash)[Ref]
Hepatic
Metabolic
Musculoskeletal
Nervous system
- Frequency not reported: Dizziness, syncope
- Postmarketing reports: Migraine, asthenia, paresthesia[Ref]
Ocular
- Postmarketing reports: Blurred vision, macular edema[Ref]
Psychiatric
Other
- Frequency not reported: Chills, edema[Ref]
Respiratory
References
1. (2017) "Product Information. Niacin (niacin)." 21st Century Healthcare Inc
2. (2017) "Product Information. Niacor (niacin)." Upsher-Smith Laboratories Inc
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- Drug class: miscellaneous antihyperlipidemic agents
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Further information
Nicotinamide side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.