Mozobil Side Effects

Generic name: plerixafor

Medically reviewed by Drugs.com. Last updated on Jun 19, 2024.

Note: This document provides detailed information about Mozobil Side Effects associated with plerixafor. Some dosage forms listed on this page may not apply specifically to the brand name Mozobil.

Applies to plerixafor: subcutaneous solution.

Serious side effects of Mozobil

Along with its needed effects, plerixafor (the active ingredient contained in Mozobil) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking plerixafor:

More common side effects

• bleeding gums
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• collection of blood under the skin
• coughing up blood
• deep, dark purple bruise
• difficulty in breathing or swallowing
• dizziness
• feeling of heat
• flushing, redness of the skin
• hard lump
• headache
• hives or welts, itching, skin rash
• increased menstrual flow or vaginal bleeding
• irritation
• nosebleeds
• pain
• paralysis
• prolonged bleeding from cuts
• red or black, tarry stools
• red or dark brown urine
• swelling
• unusually warm skin

Rare side effects

• chest tightness
• chills
• cold sweats
• confusion
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
• fainting
• fast heartbeat
• swelling around the eyes
• weakness

Incidence not known

• cough
• feeling of fullness
• pain in the left upper stomach or around the left shoulder
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• stomach pain
• unusual tiredness or weakness

Other side effects of Mozobil

Some side effects of plerixafor may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• bloated feeling
• diarrhea
• difficulty in moving
• excess air or gas in the stomach or bowels
• joint pain
• muscle pain or stiffness
• nausea
• passing gas
• trouble sleeping
• vomiting

Less common side effects

• belching
• bone pain
• difficulty having a bowel movement
• dry mouth
• general feeling of discomfort or illness
• heartburn
• increased sweating
• indigestion
• pressure in the stomach
• stomach discomfort or upset
• swelling of the abdominal or stomach area

Incidence not known

• abnormal dreams and nightmares

For healthcare professionals

Applies to plerixafor: subcutaneous solution.

Gastrointestinal adverse events

• Very common (10% or more): Diarrhea (up to 37%), nausea (up to 34%), vomiting (up to 10%)
• Common (1% to 10%): Flatulence, abdominal pain, abdominal distension, dry mouth, stomach discomfort, hypoesthesia oral, constipation, dyspepsia^[Ref]

Local

• Very common (10% or more): Injection site reactions (up to 34%)^[Ref]

Other

• Very common (10% or more): Fatigue (up to 27%)
• Common (1% to 10%): Malaise^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 22%), paresthesia (up to 20.6%), dizziness (up to 11%)
• Uncommon (0.1% to 1%): Vasovagal reactions^[Ref]

Musculoskeletal

• Very common (10% or more): Arthralgia (up to 13%)
• Common (1% to 10%): Musculoskeletal pain^[Ref]

Dermatologic

• Common (1% to 10%): Hyperhidrosis, erythema^[Ref]

Hematologic

• Common (1% to 10%): Hyperleukocytosis
• Frequency not reported: Thrombocytopenia
• Postmarketing reports: Splenomegaly and splenic rupture^[Ref]

Psychiatric

• Common (1% to 10%): Insomnia
• Uncommon (0.1% to 1%): Abnormal dreams, nightmares^[Ref]

Immunologic

• Uncommon (0.1% to 1%): Allergic reactions
• Postmarketing reports: Anaphylactic reactions including anaphylactic shock^[Ref]

Cardiovascular

• Rare (less than 0.1%): Myocardial infarction^[Ref]

Further information

Mozobil side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer