Mavik Side Effects

Generic name: trandolapril

Medically reviewed by Drugs.com. Last updated on Sep 29, 2024.

Note: This document provides detailed information about Mavik Side Effects associated with trandolapril. Some dosage forms listed on this page may not apply specifically to the brand name Mavik.

Applies to trandolapril: oral tablet.

Important warnings This medicine can cause some serious health issues

Oral route (tablet)

Discontinue trandolapril as soon as possible if the patient becomes pregnant, as drugs that target the renin-angiotensin system can cause injury and death to the developing fetus.

Serious side effects of Mavik

Along with its needed effects, trandolapril (the active ingredient contained in Mavik) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking trandolapril:

More common side effects

• blurred vision
• confusion
• difficulty with breathing
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fainting
• irregular heartbeat
• nausea
• nervousness
• numbness or tingling in the hands, feet, or lips
• stomach pain
• sweating
• unusual tiredness or weakness
• vomiting
• weakness or heaviness of the legs

Less common side effects

• chest pain or discomfort
• cool, sweaty skin
• difficulty with speaking
• double vision
• inability to move the arms, legs, or facial muscles
• muscle cramps in the hands, arms, feet, legs, or face
• numbness and tingling around the mouth
• seizures
• slow heartbeat
• stomach cramps
• tremor

Other side effects of Mavik

Some side effects of trandolapril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• belching
• cough
• heartburn
• indigestion
• stomach discomfort or upset

Less common side effects

• burning feeling in the chest or stomach
• difficulty with moving
• joint pain
• muscle aches, pain, or stiffness
• swollen joints
• tenderness in the stomach area

For healthcare professionals

Applies to trandolapril: oral tablet.

General adverse events

The most frequently reported side effects were dizziness and a dry, nonproductive cough.^[Ref]

Respiratory

• Very common (10% or more): Cough (up to 35%)
• Common (1% to 10%): Bronchitis, upper respiratory tract infections, rhinitis
• Uncommon (0.1% to 1%): Dyspnea, sore throat, hoarseness, epistaxis, throat inflammation
• Very rare (less than 0.01%): Bronchospasm, sinusitis, lung infiltration, allergic alveolitis, eosinophilic pneumonia^[Ref]

Nervous system

• Very common (10% or more): Dizziness (up to 23%)
• Common (1% to 10%): Headache
• Uncommon (0.1% to 1%): Paresthesia, vertigo, taste disturbances, sleep disturbance, insomnia, transient ischemic attacks, drowsiness, cerebral hemorrhage, somnolence
• Rare (less than 0.1%): Muscle convulsions, disturbance of balance^[Ref]

Cardiovascular

• Very common (10% or more): Hypotension (up to 11%)
• Common (1% to 10%): Orthostatic effects, syncope, bradycardia, cardiogenic shock, intermittent claudication, stroke, percutaneous transluminal coronary angioplasty, coronary artery bypass graft surgery
• Uncommon (0.1% to 1%): Myocardial infarction, cerebrovascular accident, palpitations, tachycardia, Raynaud's phenomenon, chest pain, arrhythmias, angina pectoris, cerebral hemorrhage, AV first degree block, edema, flushing
• Frequency not reported: Vasculitis
• Postmarketing reports: Myocardial ischemia, cardiac failure, ventricular tachycardia^[Ref]

Renal

• Common (1% to 10%): Renal dysfunction, elevated BUN, increased creatinine
• Uncommon (0.1% to 1%): Deterioration of renal function, acute renal failure
• Rare (0.01% to 0.1%): Uremia
• Very rare (less than 0.01%): Bacterial interstitial nephritis^[Ref]

Dermatologic

• Common (1% to 10%): Rash
• Uncommon (0.1% to 1%): Pruritus, angioedema, pemphigus, non-specific skin disorder
• Rare (0.01% to 0.1%): Hypersensitivity/angioneurotic edema, urticaria, alopecia, psoriasis
• Very rare (less than 0.01%): Diaphoresis, toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme, photosensitivity, blushing, onycholysis^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, vomiting, dyspepsia, gastritis, gastrointestinal pain
• Uncommon (0.1% to 1%): Nausea, abdominal pain, indigestion, anorexia, gastrointestinal disorder, constipation, dry mouth, abdominal distention, abdominal cramps
• Rare (0.01% to 0.1%): Loss of appetite
• Very rare (less than 0.01%): Pancreatitis, intestinal angioedema, stomatitis, glossitis^[Ref]

Metabolic

• Very common (10% or more): Increased serum uric acid (15%)
• Common (1% to 10%): Hyperkalemia, hypocalcemia
• Uncommon (0.1% to 1%): Increased blood urea, gout
• Rare (0.01% to 0.1%): Hyponatremia
• Very rare (less than 0.01%): Hypoglycemia^[Ref]

Hematologic

• Uncommon (0.1% to 1%): Decreased leukocytes, decreased neutrophils
• Rare (0.01% to 0.1%): Decreased hemoglobin, decreased hematocrit
• Very rare (less than 0.01%): Bone marrow depression, anemia, thrombocytopenia, leukopenia, neutropenia, eosinophilia, agranulocytosis, hemolytic anemia, lymphadenopathy, autoimmune disease
• Frequency not reported: Elevated red blood cell sedimentation rate (ESR), leukocytosis
• Postmarketing reports: Pancytopenia, decreased platelets^[Ref]

Musculoskeletal

• Common (1% to 10%): Myalgia
• Uncommon (0.1% to 1%): Muscle cramps, pain in extremities
• Frequency not reported: Arthralgia, arthritis^[Ref]

Genitourinary

• Common (1% to 10%): Urinary infection
• Uncommon (0.1% to 1%): Impotence, decreased libido
• Rare (0.01% to 0.1%): Proteinuria
• Very rare (less than 0.01%): Oliguria, anuria^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Increased liver enzymes
• Rare (0.01% to 0.1%): Increased serum bilirubin
• Very rare (less than 0.01%): Hepatocellular or cholestatic hepatitis, jaundice^[Ref]

Hypersensitivity

• Postmarketing reports: Allergic hypersensitivity reactions (including pruritus and rash)^[Ref]

Other

• Common (1% to 10%): Fatigue, influenza-like syndrome, asthenia, malaise
• Uncommon (0.1% to 1%): Abnormal feeling
• Rare (less than 0.1%): Tinnitus
• Postmarketing reports: Fever^[Ref]

Psychiatric

• Uncommon (0.1% to 1%): Mood alterations, anxiety, depression
• Rare (less than 0.1%): Mental confusion, nervousness
• Postmarketing reports: Hallucinations^[Ref]

Endocrine

• Rare (less than 0.1%): Gynecomastia^[Ref]

Ocular

• Rare (less than 0.1%): Blurred vision^[Ref]

Immunologic

• Frequency not reported: Positive antinuclear antibodies (ANA)^[Ref]

Further information

Mavik side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer