Lodrane XR Side Effects

Generic name: brompheniramine

Note: This document provides detailed information about Lodrane XR Side Effects associated with brompheniramine. Some dosage forms listed on this page may not apply specifically to the brand name Lodrane XR.

Applies to brompheniramine: compounding powder, injectable solution, oral capsule, oral capsule extended release, oral liquid, oral suspension extended release, oral tablet, oral tablet chewable extended release, oral tablet extended release.

Important warnings This medicine can cause some serious health issues

Ask a doctor or pharmacist before using this medicine if you have health problems or use other medications, or if you are pregnant or breastfeeding.

Do not use cold or allergy medicine to make a child sleepy.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using brompheniramine (the active ingredient contained in Lodrane XR) and call your doctor at once if you have:

• extreme drowsiness;

• confusion, hallucinations;

• feeling nervous, restless, or dizzy;

• a seizure; or

• little or no urination.

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

Common side effects may include:

• drowsiness;

• blurred vision;

• constipation;

• flushing (warmth, redness, or tingly feeling);

• dry mouth, nose, or throat; or

• feeling restless or excited (especially in a child).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to brompheniramine: compounding powder, injectable solution, oral capsule, oral capsule extended release, oral liquid, oral suspension extended release, oral tablet, oral tablet chewable extended release, oral tablet extended release.

Nervous system

Nervous system side effects have included central nervous system (CNS) depression, resulting in drowsiness and sedation in nearly 50% of patients treated. This effect has often been transient and ceased with continued use. Motor skills have be impaired and patients should be advised to avoid tasks which require attention. Patients should also avoid concomitant use with alcohol and other sedative-hypnotic drugs. Dyskinesias have rarely been reported following chronic use of brompheniramine (the active ingredient contained in Lodrane XR) ^[Ref]

A few cases of dyskinesias and tremors, often of the face, have been reported in patients whose chronic use of brompheniramine extended over a period of up to 10 years. Some of these cases were only partially relieved by discontinuation of the drug. Haloperidol was successful in relieving symptoms in these patients. Spasmodic torticollis has been reported in a child given brompheniramine over an eight month period.^[Ref]

Gastrointestinal

Gastrointestinal side effects have include nausea, dry mouth and constipation.^[Ref]

Cardiovascular

Cardiovascular effects of brompheniramine (the active ingredient contained in Lodrane XR) have included hypotension, tachycardia, and palpitations.^[Ref]

Ocular

Ocular side effects have included blurred vision, diplopia, and dry eyes due to anticholinergic effects.^[Ref]

Genitourinary

Genitourinary side effects have included dysuria, urinary hesitancy, decrease in urine flow, and, in rare cases, acute urinary retention.^[Ref]

Hematologic

Hematologic side effects have included rare cases of hemolytic anemia, thrombocytopenia, and agranulocytosis.^[Ref]

Further information

Lodrane XR side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer