Levothyroxine / Liothyronine Side Effects

Applies to levothyroxine/liothyronine: oral tablet.

General adverse events

Adverse reactions other than those attributable to hyperthyroidism due to therapeutic overdose are rare. Excessive doses may result in a hypermetabolic state resembling in every respect the condition of endogenous origin.^[Ref]

Endocrine

• Postmarketing reports: Hypothyroidism, thyroid stimulating hormone (TSH) increased, TSH decreased^[Ref]

Cardiovascular

• Postmarketing reports: Palpitation, blood pressure increased, heart rate increased^[Ref]

Dermatologic

• Postmarketing reports: Alopecia, dry skin, urticaria, hyperhidrosis, pruritus^[Ref]

Immunologic

• Postmarketing reports: Hypersensitivity^[Ref]

Musculoskeletal

• Postmarketing reports: Arthralgia, myalgia^[Ref]

Ocular

• Postmarketing reports: Keratoconjunctivitis sicca^[Ref]

Other

• Postmarketing reports: Fatigue, sluggishness, weight increased, asthenia, chest pain^[Ref]

Nervous system

• Postmarketing reports: Headache, tremor^[Ref]

Gastrointestinal

• Postmarketing reports: Nausea^[Ref]

Psychiatric

• Postmarketing reports: Anxiety, depression, insomnia^[Ref]

Further information

Levothyroxine/liothyronine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer