Isopto Homatropine Side Effects

Generic name: homatropine ophthalmic

Medically reviewed by Drugs.com. Last updated on Jul 22, 2024.

Note: This document provides detailed information about Isopto Homatropine.

Applies to homatropine ophthalmic: ophthalmic solution Side Effects associated with homatropine ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Isopto Homatropine.

Applies to homatropine ophthalmic: ophthalmic solution.

Side effects include:

Elevated IOP, transient stinging, burning. With prolonged administration, local irritation (characterized by follicular conjunctivitis, vascular congestion, edema, exudate, and eczematoid dermatitis ), thirst, dry mouth, increased light sensitivity of eyes.

For healthcare professionals

Applies to homatropine ophthalmic: compounding powder, ophthalmic solution.

General adverse events

The most frequently reported side effects were transient stinging/burning upon instillation and increased sensitivity to light.^[Ref]

Ocular

• Common (1% to 10%): Transient burning, transient stinging, increased sensitivity to light
• Uncommon (0.1% to 1%): Eye irritation
• Rare (0.01% to 0.1%): Local irritation, vascular congestion, edema, exudates, eczematoid dermatitis, follicular conjunctivitis
• Postmarketing reports: Conjunctivitis, photophobia, mydriasis prolonged, eye pain, eye edema, eye discharge, eye irritation, ocular hyperemia^[Ref]

Gastrointestinal

• Rare (0.01% to 0.1%): Thirst, dryness of mouth
• Frequency not reported: Abdominal distention infants, gastrointestinal motility diminished, salivary secretion decreased, sweat gland secretion decreased^[Ref]

Nervous system

• Frequency not reported: Ataxia, incoherent speech, hyperactivity, seizure, unusual drowsiness
• Postmarketing reports: Somnolence^[Ref]

Psychiatric

• Frequency not reported: Restlessness, hallucination, disorientation, failure to recognize people
• Postmarketing reports: Confusion^[Ref]

Genitourinary

• Frequency not reported: Urinary retention^[Ref]

Respiratory

• Frequency not reported: Secretion decreased in pharynx/bronchi/nasal passages, rapidly progressive respiratory depression^[Ref]

Other

• Frequency not reported: Hyperpyrexia^[Ref]

Cardiovascular

• Frequency not reported: Tachycardia, vasodilation, hypotension
• Postmarketing reports: Heart rate increased^[Ref]

Dermatologic

• Frequency not reported: Skin rash^[Ref]

Further information

Isopto Homatropine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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