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Granix Side Effects

Generic name: tbo-filgrastim

Medically reviewed by Drugs.com. Last updated on Jun 3, 2024.

Note: This document provides detailed information about Granix Side Effects associated with tbo-filgrastim. Some dosage forms listed on this page may not apply specifically to the brand name Granix.

Applies to tbo-filgrastim: subcutaneous solution.

Serious side effects of Granix

Along with its needed effects, tbo-filgrastim (the active ingredient contained in Granix) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking tbo-filgrastim:

More common side effects

  • black, tarry stools
  • bleeding gums
  • blood in the urine or stools
  • bone pain
  • fever
  • pinpoint red spots on the skin
  • unusual bleeding or bruising

Rare side effects

  • chills
  • cough
  • eye pain
  • general feeling of illness
  • headache
  • sore throat
  • unusual tiredness

Incidence not known

  • blisters or fever sores on the skin
  • bloody or cloudy urine
  • chest pain or tightness
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives, itching, or skin rash
  • pain in the upper left part of the stomach or at the tip of the left shoulder
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • trouble breathing
  • unusual weakness
  • weight gain

Other side effects of Granix

Some side effects of tbo-filgrastim may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

Incidence not known

  • bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • lack or loss of strength

Managing side effects (general information)

For healthcare professionals

Applies to tbo-filgrastim: subcutaneous solution.

Cardiovascular adverse events

In a clinical trial, thrombocytopenia occurred in 34% of pediatric patients (n=50) given 5 mcg/kg subcutaneously once a day starting one day after chemotherapy.

Gastrointestinal

In a clinical trial, diarrhea occurred in 6% of pediatric patients (n=50) given 5 mcg/kg subcutaneously once a day starting one day after chemotherapy.[Ref]

Musculoskeletal

In a clinical trial, extremity pain occurred in 6% of pediatric patients (n=50) given 5 mcg/kg subcutaneously once a day starting one day after chemotherapy.[Ref]

Other

In a clinical trial, pyrexia occurred in 8% of pediatric patients (n=50) given 5 mcg/kg subcutaneously once a day starting one day after chemotherapy.[Ref]

Nervous system

In a clinical trial, headache occurred in 6% of pediatric patients (n=50) given 5 mcg/kg subcutaneously once a day starting one day after chemotherapy.

Immunologic

Hematologic

Dermatologic

Oncologic

Hypersensitivity

Respiratory

Renal

References

1. (2013) "Product Information. Granix (tbo-filgrastim)." Teva Pharmaceuticals USA

Further information

Granix side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer