Frovatriptan Side Effects

Medically reviewed by Drugs.com. Last updated on Aug 6, 2024.

Applies to frovatriptan: oral tablet.

Serious side effects of frovatriptan

Along with its needed effects, frovatriptan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking frovatriptan:

Other side effects of frovatriptan

Some side effects of frovatriptan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to frovatriptan: oral tablet.

General adverse events

The most commonly reported adverse events included dizziness, fatigue, paraesthesia, headache, and vascular flushing.^[Ref]

Hypersensitivity

• Postmarketing reports: Hypersensitivity reactions including cutaneous disorders, angioedema, and anaphylactic reactions^[Ref]

Cardiovascular

• Common (1% to 10%): Flushing, chest discomfort
• Uncommon (0.1% to 1%): Palpitations, tachycardia, peripheral coldness, hypertension, chest pain
• Rare (0.01% to 0.1%): Bradycardia
• Postmarketing reports: Myocardial infarction, coronary arteriospasm^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, headache, paresthesia, dysesthesia, hypoesthesia , somnolence
• Uncommon (0.1% to 1%): Dysgeusia, tremor, disturbance in attention. lethargy, sedation, vertigo, involuntary muscle contractions
• Rare (0.01% to 0.1%): Amnesia hypertonia hypotonia, hyporeflexia, movement disorder
• Postmarketing reports: Seizure^[Ref]

Psychiatric

• Uncommon (0.1% to 1%): Anxiety, insomnia, confusional state, nervousness, agitation, depression, depersonalization
• Rare (0.01% to 0.1%): Abnormal dreams, personality disorder^[Ref]

Gastrointestinal

• Common (1% to 10%): Dry mouth, dyspepsia, vomiting, nausea, abdominal pain, diarrhea
• Uncommon (0.1% to 1%): Dysphagia, flatulence, constipation, anorexia, esophagospasm, increased salivation
• Rare (0.01% to 0.1%): Change in bowel habits, chelitis, eructation, gastroesophageal reflux, hiccough, peptic ulcer, salivary gland pain, stomatitis, toothache, lip blister, lip pain , oral mucosal blistering, peptic ulcer, salivary gland pain^[Ref]

Musculoskeletal

• Common (1% to 10%): Skeletal pain
• Uncommon (0.1% to 1%): Musculoskeletal stiffness, musculoskeletal pain, pain in extremity, back pain, arthralgia^[Ref]

Respiratory

• Common (1% to 10%): Throat tightness
• Uncommon (0.1% to 1%): Rhinitis, sinusitis, pharyngolaryngeal pain
• Rare (0.01% to 0.1%): Epistasis, hiccups, hyperventilation, respiratory disorder, throat irritation^[Ref]

Ocular

• Common (1% to 10%): Visual disturbance
• Uncommon (0.1% to 1%): Eye pain, eye irritation, photophobia
• Rare (0.01% to 0.1%): Night blindness^[Ref]

Dermatologic

• Common (1% to 10%): Hyperhidrosis
• Uncommon (0.1% to 1%): Pruritus
• Rare (0.01% to 0.1%): Erythema, piloerection, urticaria, purpura^[Ref]

Other

• Common (1% to 10%): Fatigue, hot or cold sensation, tinnitus
• Uncommon (0.1% to 1%): Ear pain, ear discomfort, ear disorder, ear pruritus, hyperacusis, feeling hot temperature intolerance, asthenia, sluggishness, energy increased, malaise
• Rare (0.01% to 0.1%): Pyrexia^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Increased micturition frequency, polyuria
• Rare (0.01% to 0.1%): Nocturia, renal pain, abnormal urine analysis^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Dehydration, thirst
• Rare (0.01% to 0.1%): Hypoglycemia^[Ref]

Hematologic

• Rare (0.01% to 0.1%): Lymphadenopathy^[Ref]

Hepatic

• Rare (0.01% to 0.1%): Increased blood bilirubin^[Ref]

Endocrine

• Uncommon (0.1% to 1%): Breast tenderness^[Ref]

Further information

Frovatriptan side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

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