Egaten Side Effects

Generic name: triclabendazole

Medically reviewed by Drugs.com. Last updated on Jan 18, 2025.

Note: This document provides detailed information about Egaten Side Effects associated with triclabendazole. Some dosage forms listed on this page may not apply specifically to the brand name Egaten.

Applies to triclabendazole: oral tablet.

Serious side effects of Egaten

Along with its needed effects, triclabendazole (the active ingredient contained in Egaten) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking triclabendazole:

More common side effects

• dizziness or lightheadedness
• feeling of constant movement of self or surroundings
• sensation of spinning

Less common side effects

• back pain
• chest pain, discomfort, or tightness
• cough
• difficulty breathing
• fever
• nausea
• upper right abdominal or stomach pain
• vomiting
• yellow skin or eyes

Other side effects of Egaten

Some side effects of triclabendazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• decreased appetite
• diarrhea
• headache
• increased sweating
• skin rash
• stomach pain

Less common side effects

• abnormal color of urine
• back pain
• constipation
• difficulty in moving
• itching
• joint pain
• lack or loss of strength
• muscle pain or stiffness

For healthcare professionals

Applies to triclabendazole: oral tablet.

Gastrointestinal adverse events

• Very common (10% or more): Abdominal pain (included upper abdominal pain, abdominal pain; up to 93%), nausea (up to 18%)
• Common (1% to 10%): Vomiting, diarrhea
• Frequency not reported: Constipation^[Ref]

Some side effects associated with this drug treatment in fascioliasis (e.g., abdominal pain) could be secondary to the infection; such effects may be more severe and/or may occur more often in patients with heavy worm burden.^[Ref]

Dermatologic

• Very common (10% or more): Hyperhidrosis (up to 25%), urticaria (up to 11%)
• Common (1% to 10%): Pruritus^[Ref]

Metabolic

• Very common (10% or more): Decreased appetite (up to 18%)^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 14%)
• Common (1% to 10%): Vertigo^[Ref]

Hepatic

• Common (1% to 10%): Elevated bilirubin, elevated AST, elevated ALT, jaundice (included jaundice, ocular icterus)
• Frequency not reported: Biliary colic, transient increases in liver enzymes, transient increases in total bilirubin

Posttreatment elevations in bilirubin, AST, and ALT were reported in 6.8%, 4.5%, and 3% of patients with normal liver enzyme values at baseline, respectively.

Some side effects associated with this drug treatment in fascioliasis (e.g., biliary colic, jaundice) could be secondary to the infection; such effects may be more severe and/or may occur more often in patients with heavy worm burden.

Respiratory

• Common (1% to 10%): Dyspnea, cough^[Ref]

Other

• Common (1% to 10%): Elevated alkaline phosphatase, asthenia, chest pain, pyrexia, chest discomfort
• Postmarketing reports: Drug resistance^[Ref]

Posttreatment elevations in alkaline phosphatase were reported in 4.2% of patients with normal liver enzyme values at baseline.

Resistance to this drug has been reported outside the US.^[Ref]

Musculoskeletal

• Common (1% to 10%): Musculoskeletal chest pain
• Frequency not reported: Arthralgia, back pain, spinal pain^[Ref]

Genitourinary

• Frequency not reported: Chromaturia^[Ref]

Further information

Egaten side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer