Dutasteride Side Effects
Medically reviewed by Drugs.com. Last updated on Nov 11, 2023.
Applies to dutasteride: oral capsule liquid filled.
Common side effects of dutasteride
Some side effects of dutasteride may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
- abnormal ejaculation
- decreased interest in sexual intercourse
- decreased sexual performance or desire
- impotence
- inability to have or keep an erection
- loss in sexual ability, desire, drive, or performance
- pain, soreness, swelling, or discharge from the breast or breasts
Serious side effects of dutasteride
Along with its needed effects, dutasteride may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking dutasteride:
Rare
- chest pain or discomfort
- dilated neck veins
- extreme fatigue
- irregular breathing
- irregular heartbeat
- swelling of the face, fingers, feet, or lower legs
- trouble breathing
- weight gain
Incidence not known
- blistering, flaking, or peeling of the skin
- cough
- difficulty with swallowing
- dizziness
- fast heartbeat
- hives or welts, itching skin, rash
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness of the skin
- tightness in the chest
- unusual tiredness or weakness
For healthcare professionals
Applies to dutasteride: oral capsule.
Other
- Common (1% to 10%): Impotence, decreased libido, ejaculation disorders, breast disorders
- Postmarketing reports: Testicular pain and swelling[Ref]
Impotence, decreased libido, and ejaculation disorders may persist after treatment discontinuation; this drug's role in this persistence is unknown.
Ejaculation disorders included anorgasmia, retrograde ejaculation, decreased semen volume, decreased orgasmic sensation, abnormal orgasm, delayed ejaculation, ejaculation failure, and premature ejaculation.
Breast disorders include breast enlargement, gynecomastia, breast swelling, breast pain, breast tenderness, nipple pain, and nipple swelling.[Ref]
Oncologic
- Common (1% to 10%): High-grade prostate cancer
- Frequency not reported: Male breast cancer[Ref]
Cardiovascular
- Uncommon (0.1% to 1%): Cardiac failure[Ref]
Dermatologic
Nervous system
- Uncommon (0.1% to 1%): Dizziness, nervous system disorders[Ref]
Hypersensitivity
- Postmarketing reports: Hypersensitivity reactions (e.g., rash, pruritus, urticaria, localized edema, serious skin reactions, angioedema)[Ref]
Psychiatric
- Postmarketing reports: Depressed mood[Ref]
References
1. (2002) "Product Information. Duagen (dutasteride)." GlaxoSmithKline Healthcare
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Further information
Dutasteride side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.