Dextrostat Side Effects

Generic name: dextroamphetamine

Medically reviewed by Drugs.com. Last updated on Aug 20, 2024.

Note: This document provides detailed information about Dextrostat Side Effects associated with dextroamphetamine. Some dosage forms listed on this page may not apply specifically to the brand name Dextrostat.

Applies to dextroamphetamine: transdermal patch extended release.

Other dosage forms:

• oral capsule extended release, oral solution, oral tablet

Important warnings This medicine can cause some serious health issues

Transdermal route (patch, extended release)

Abuse, Misuse, and Addiction. Dextroamphetamine has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction.

Misuse and abuse of CNS stimulants, including dextroamphetamine, can result in overdose and death, and this risk is increased with higher doses or unapproved methods of administration, such as snorting or injection.Before prescribing dextroamphetamine, assess each patient’s risk for abuse, misuse, and addiction.

Educate patients and their families about these risks, proper storage of the drug, and proper disposal of any unused drug.

Throughout dextroamphetamine treatment, reassess each patient’s risk of abuse, misuse, and addiction and frequently monitor for signs and symptoms of abuse, misuse, and addiction.

Serious side effects of Dextrostat

Along with its needed effects, dextroamphetamine (the active ingredient contained in Dextrostat) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dextroamphetamine:

More common side effects

• black, tarry stools
• chills
• cough
• fever
• lower back or side pain
• painful or difficult urination
• pale skin
• sore throat
• trouble breathing
• ulcers, sores, or white spots in the mouth
• unusual bleeding or bruising
• unusual tiredness or weakness

Less common side effects

• increased heart rate
• increase in blood pressure

Incidence not known

• anger
• bladder pain
• blistering, burning, crusting, dryness, flaking, peeling, or loosening of the skin
• bloody nose
• bloody or cloudy urine
• bloody vomit
• blurred vision
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• chest pain, discomfort, or tightness
• dark urine
• delusions of persecution, mistrust, suspiciousness, or combativeness
• diarrhea
• difficulty in speaking
• discouragement
• dizziness
• fast, slow, pounding, or irregular heartbeat or pulse
• fear, nervousness
• feeling sad or empty
• frequent urge to urinate
• hives, itching, skin rash
• irritability
• joint or muscle pain
• lack of appetite
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• light-colored stools
• loss of interest or pleasure
• mood swings
• muscle cramps, spasms, pain, or stiffness
• nausea
• pain or discomfort in the arms, jaw, back, or neck
• paleness or cold feeling in the fingertips and toes
• pounding in the ears
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• red irritated eyes
• red skin lesions, often with a purple center
• restlessness
• scaling, severe redness, soreness, or swelling of the skin
• seizures
• severe stomach pain
• shakiness in the legs, arms, hands, or feet
• sleepiness or unusual drowsiness
• sweating
• swelling of the feet or lower legs
• tingling or pain in the fingers or toes when exposed to cold
• trembling or shaking of the hands or feet
• trouble concentrating
• trouble sleeping
• twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
• upper right abdominal or stomach pain
• vomiting
• weight decreased
• yellow eyes and skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking dextroamphetamine:

Symptoms of overdose

• aggressive
• agitation
• angry
• blurred vision
• change in consciousness
• chest pain or discomfort
• confusion
• diarrhea
• dark urine
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fainting
• fast breathing
• fast, slow, or irregular heartbeat
• fever
• headache
• inability to speak
• loss of consciousness
• muscle cramps, spasms, pain, or stiffness
• nausea
• nervousness
• overactive reflexes
• pain or discomfort in the arms, jaw, back, or neck
• pale, clammy skin
• palpitations
• pounding in the ears
• restlessness
• seeing, hearing, or feeling things that are not there
• seizures
• shivering
• slow or fast heartbeat
• slurred speech
• stomach cramps
• sweating
• talking or acting with excitement you cannot control
• temporary blindness
• thirst
• tremor
• trouble breathing
• unusual tiredness or weakness
• vomiting

Other side effects of Dextrostat

Some side effects of dextroamphetamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• decreased appetite
• headache

Incidence not known

• bigger, dilated, or enlarged pupils (black part of eye)
• change in taste
• constipation
• decreased interest in sexual intercourse
• double vision
• inability to have or keep an erection
• increased sensitivity of the eyes to light
• loss in sexual ability, desire, drive, or performance
• loss of taste
• loss or thinning of the hair
• seeing double

For healthcare professionals

Applies to dextroamphetamine: oral capsule extended release, oral solution, oral tablet, transdermal film.

Metabolic adverse events

• Very common (10% or more): Decreased appetite, reduced weight gain, weight loss
• Common (1% to 10%): Anorexia
• Frequency not reported: Acidosis^[Ref]

Psychiatric

• Very common (10% or more): Insomnia, nervousness
• Common (1% to 10%): Abnormal behavior, aggression/hostility, excitation, anxiety, depression, irritability
• Uncommon (0.1% to 1%): Psychotic episodes/psychosis
• Very rare (less than 0.01%): Suicidal behavior (including completed suicide), mania, hallucinations
• Frequency not reported: Overstimulation, restlessness, euphoria, dysphoria, confusion, dependence, emotional lability, impaired cognitive test performance, altered libido, night terrors, obsessive-compulsive behavior, panic states, paranoia^[Ref]

Cardiovascular

• Common (1% to 10%): Arrhythmia, palpitations, tachycardia
• Rare (less than 0.1%): Angina pectoris
• Very rare (less than 0.01%): Cardiac arrest
• Frequency not reported: Blood pressure and heart rate changes (usually elevated), cardiomyopathy, myocardial infarction, chest pain, cardiovascular collapse, Raynaud's phenomenon^[Ref]

Gastrointestinal

• Common (1% to 10%): Abdominal pain and cramps, nausea, vomiting, dry mouth
• Frequency not reported: Ischemic colitis, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances^[Ref]

Musculoskeletal

• Common (1% to 10%): Arthralgia
• Rare (less than 0.1%): Growth retardation
• Very rare (less than 0.01%): Muscle cramps
• Frequency not reported: Rhabdomyolysis^[Ref]

Nervous system

• Common (1% to 10%): Vertigo, dyskinesia, headache, hyperactivity
• Very rare (less than 0.01%): Tourette syndrome, tics, exacerbation of pre-existing motor and phonic tics, convulsions, choreoathetoid movements, intracranial hemorrhage, cerebral vasculitis and/or occlusion, neuroleptic malignant syndrome (NMS)
• Frequency not reported: Dizziness, tremor, ataxia, dysgeusia, concentration difficulties, hyperreflexia, stroke^[Ref]

Dermatologic

• Rare (less than 0.1%): Rash, urticaria
• Very rare (less than 0.01%): Erythema multiforme, exfoliative dermatitis, fixed drug eruption
• Frequency not reported: Sweating, alopecia^[Ref]

Ocular

• Rare (less than 0.1%): Visual accommodation difficulties, blurred vision, mydriasis^[Ref]

Other

• Rare (less than 0.1%): Fatigue
• Frequency not reported: Hyperpyrexia, sudden death^[Ref]

Hematologic

• Very rare (less than 0.01%): Anemia, leukopenia, thrombocytopenia, thrombocytopenic purpura^[Ref]

Hepatic

• Very rare (less than 0.01%): Abnormal liver function ranging from hepatic enzyme elevations to hepatic coma^[Ref]

Endocrine

• Frequency not reported: Impotence, libido changes, frequent or prolonged erections^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity reactions (e.g., angioedema and anaphylaxis)^[Ref]

Renal

• Frequency not reported: Renal damage^[Ref]

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Further information

Dextrostat side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer