Clevidipine Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 18, 2024.

Applies to clevidipine: intravenous emulsion.

Serious side effects of clevidipine

Along with its needed effects, clevidipine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking clevidipine:

More common side effects

• agitation
• confusion
• decreased urine output
• depression
• dizziness
• fainting
• fast or irregular heartbeat
• headache
• hostility
• irritability
• lethargy
• loss of consciousness
• muscle twitching
• nausea
• rapid weight gain
• seizures (convulsions)
• stupor
• swelling of the face, ankles, or hands
• unusual tiredness or weakness

Rare side effects

• chest pain or discomfort
• difficult or labored breathing
• pain or discomfort in the arms, jaw, back, or neck
• shortness of breath
• stopping of the heart
• sweating
• tightness in the chest
• unconsciousness
• very low blood pressure or pulse
• vomiting
• wheezing

For healthcare professionals

Applies to clevidipine: intravenous emulsion.

General adverse events

Atrial fibrillation, sinus tachycardia, and hypotension were frequently observed in the perioperative population.^[Ref]

Cardiovascular

• Very common (10% or more): Atrial fibrillation (up to 32.9%), sinus tachycardia (up to 30.5%), hypotension (up to 15.1%)
• Common (1% to 10%): Flushing
• Uncommon (0.1% to 1%): Atrial flutter, tachycardia, congestive heart failure, bradycardia, complete atrioventricular block, bundle branch block
• Frequency not reported: Myocardial infarction, cardiac arrest
• Postmarketing reports: Reflex tachycardia^[Ref]

Gastrointestinal

• Very common (10% or more): Nausea (up to 21%)
• Common (1% to 10%): Vomiting
• Uncommon (0.1% to 1%): Constipation
• Rare (less than 0.1%): Ileus^[Ref]

Nervous system

• Common (1% to 10%): Headache
• Uncommon (0.1% to 1%): Dizziness
• Frequency not reported: Syncope^[Ref]

Other

• Common (1% to 10%): Edema, chest pain, feeling hot^[Ref]

Metabolic

• Common (1% to 10%): Oxygen saturation decreased
• Postmarketing reports: Blood triglycerides increased^[Ref]

Renal

• Common (1% to 10%): Acute renal failure^[Ref]

Genitourinary

• Common (1% to 10%): Polyuria^[Ref]

Respiratory

• Uncommon (0.1% to 1%): Pulmonary congestion
• Frequency not reported: Dyspnea^[Ref]

Immunologic

• Uncommon (0.1% to 1%): Hypersensitivity^[Ref]

Further information

Clevidipine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer