Cemill 1000 Side Effects

Generic name: ascorbic acid

Medically reviewed by Drugs.com. Last updated on May 4, 2024.

Note: This document provides detailed information about Cemill 1000 Side Effects associated with ascorbic acid. Some dosage forms listed on this page may not apply specifically to the brand name Cemill 1000.

Applies to ascorbic acid: oral capsule, oral capsule extended release, oral liquid, oral powder, oral powder for solution, oral powder for suspension, oral solution, oral tablet, oral tablet chewable, oral tablet extended release, oral wafer.

Other dosage forms:

• intravenous solution

Serious side effects of Cemill 1000

Along with its needed effects, ascorbic acid (the active ingredient contained in Cemill 1000) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking ascorbic acid:

Less common or rare side effects

- with high doses

• Side or lower back pain

Other side effects of Cemill 1000

Some side effects of ascorbic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare side effects

- with high doses

• Diarrhea
• dizziness or faintness (with the injection only)
• flushing or redness of skin
• headache
• increase in urination (mild)
• nausea or vomiting
• stomach cramps

For healthcare professionals

Applies to ascorbic acid: compounding powder, injectable solution, intravenous solution, oral capsule, oral capsule extended release, oral gum, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release.

Renal adverse events

Renal side effects have included oxalate and urate kidney stones.^[Ref]

Hyperoxaluria appears to be dose-related.^[Ref]

Nervous system

Nervous system side effects have included dizziness, faintness, fatigue, and headache in less than 1% of patients. Migraine headache has also been reported.^[Ref]

Migraine headache has been reported with a daily dose of 6 grams.

The manufacturer reports temporary dizziness and faintness may be associated with too rapid of a rate during intravenous administration.^[Ref]

Other

Other side effects have included flank pain in less than 1% of patients. Conditional scurvy has also been reported.^[Ref]

Conditional scurvy is reported to occur following excessive doses of ascorbic acid over a prolonged period of time. The mechanism of action for this condition is thought to be that large doses of ascorbic acid condition the patient over time for rapid clearance of ascorbic acid resulting in scurvy. The plasma levels of ascorbic acid appear to remain within normal limits. The actual existence of conditional scurvy remains controversial.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea, diarrhea, abdominal cramps, and esophagitis.^[Ref]

Nausea, diarrhea, and abdominal cramps appears to be associated with doses exceeding 2 g per day, although there have been some reports with as little as 1 g per day.

Esophagitis appears to be associated with prolonged or increased contact of ascorbic acid tablets with the esophageal mucosa.^[Ref]

Hematologic

Hematologic side effects have included hemolysis.^[Ref]

The majority of hemolysis reports have been associated with patients who have concurrent glucose-6-phosphate dehydrogenase deficiency.^[Ref]

Local

Local side effects have included transient mild soreness at the site of injection.^[Ref]

Further information

Cemill 1000 side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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