Brompheniramine / Codeine / Pseudoephedrine Side Effects

Medically reviewed by Drugs.com. Last updated on Feb 16, 2024.

Applies to brompheniramine/codeine/pseudoephedrine: oral liquid.

Important warnings This medicine can cause some serious health issues

Codeine may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days.

A dangerous drug interaction could occur.

MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This medicine is not for use in anyone under 18.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medications, codeine can slow your breathing. Death may occur if breathing becomes too weak. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Stop using brompheniramine, codeine, and pseudoephedrine and call your doctor at once if you have:

• severe dizziness or drowsiness, feeling like you might pass out;

• confusion, mood changes, hallucinations, unusual thoughts or behavior;

• severe nervousness, fast or uneven heart rate, tremor, seizure (convulsions);

• pain or numbness in the arms or legs;

• severe stomach cramps or constipation;

• weak or shallow breathing;

• little or no urinating;

• easy bruising or bleeding, unusual weakness; or

• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain).

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

Common side effects may include:

• dizziness, drowsiness;

• dry mouth, nose, or throat;

• constipation; or

• feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to brompheniramine / codeine / pseudoephedrine: oral liquid.

Hypersensitivity

• Frequency not reported: Anaphylactic shock, excessive perspiration, chills

Respiratory

• Frequency not reported: Thickening of bronchial secretions, tightness of chest, wheezing, nasal stuffiness, and dryness of mouth, nose and throat

Cardiovascular

• Frequency not reported: Hypotension, palpitations, tachycardia, extra systoles

Nervous system

• Frequency not reported: Sedation, dizziness, sleepiness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesias, vertigo, hysteria, neuritis, tinnitus, acute labyrinthitis, convulsions^[Ref]

Hematologic

• Frequency not reported: Hemolytic anemia, thrombocytopenia, agranulocytosis

Gastrointestinal

• Frequency not reported: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation

Genitourinary

• Frequency not reported: Urinary frequency, difficult urination, urinary retention, early menses

Ocular

• Frequency not reported: Blurred vision, diplopia

Dermatologic

• Frequency not reported: Urticaria, drug rash, photosensitivity, pruritus

Further information

Brompheniramine/codeine/pseudoephedrine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer