Azelastine Nasal Side Effects

Medically reviewed by Drugs.com. Last updated on Jul 31, 2024.

Applies to azelastine nasal: nasal spray.

Serious side effects of azelastine nasal

Along with its needed effects, azelastine nasal may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking azelastine nasal:

More common side effects

• heavy nosebleeds

Less common side effects

• burning or discomfort inside the nose
• ear congestion
• chills
• cough
• fever
• sore throat
• body aches or pain
• headache
• loss of voice
• trouble breathing
• unusual tiredness or weakness

Rare side effects

• blood in the urine
• blurred vision or other change in vision
• chest tightness
• eye pain or redness
• hives, itching, or skin rash
• rapid heartbeat
• sores in the mouth or on the lips

Other side effects of azelastine nasal

Some side effects of azelastine nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• bitter taste in the mouth
• drowsiness or sleepiness

Less common side effects

• bloody mucus or unexplained nosebleeds
• dizziness
• dryness of the mouth
• muscle aches or pain
• nausea
• sudden outbursts of sneezing
• weight gain

For healthcare professionals

Applies to azelastine nasal: nasal spray.

General adverse events

The most commonly reported adverse reactions were headache, bitter taste, sinusitis, and epistaxis.^[Ref]

Respiratory

• Common (1% to 10%): Epistaxis, nasal discomfort, upper respiratory infection, sneezing, nasal mucosal ulceration, sinusitis
• Postmarketing reports: Nasal burning, throat irritation, dyspnea, paroxysmal sneezing^[Ref]

Hypersensitivity

• Postmarketing reports: Anaphylactoid reaction^[Ref]

Local

• Postmarketing reports: Application site irritation^[Ref]

Nervous system

• Very common (10% or more): Bitter taste (10%)
• Common (1% to 10%): Headache, somnolence, dysgeusia
• Postmarketing reports: Sweet taste, confusion, dizziness, nervousness, paraesthesia, parosmia, involuntary muscle contractions, disturbance or loss of sense of smell and/or taste^[Ref]

Cardiovascular

• Postmarketing reports: Atrial fibrillation, chest pain, hypertension, palpitations, tachycardia^[Ref]

Dermatologic

• Very rare (less than 0.01%): Urticaria, pruritus, rash^[Ref]

Gastrointestinal

• Postmarketing reports: Abdominal pain, nausea^[Ref]

Other

• Common (1% to 10%): Fatigue
• Postmarketing reports: Facial edema, tolerance^[Ref]

Ocular

• Postmarketing reports: Blurred vision, xerophthalmia^[Ref]

Genitourinary

• Postmarketing reports: Urinary retention^[Ref]

Further information

Azelastine nasal side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer