Skip to main content

Amyl Nitrite Side Effects

Medically reviewed by Drugs.com. Last updated on Jan 15, 2025.

Applies to amyl nitrite: inhalation solution.

Common side effects of amyl nitrite

Some side effects of amyl nitrite may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • dizziness or lightheadedness, especially when getting up from a lying or sitting position
  • fast pulse
  • flushing of face and neck
  • headache (mild)
  • nausea or vomiting
  • restlessness

Serious side effects of amyl nitrite

Along with its needed effects, amyl nitrite may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking amyl nitrite:

Rare side effects

  • skin rash
  • unusual tiredness or weakness

Signs and symptoms of overdose

Managing side effects (general information)

For healthcare professionals

Applies to amyl nitrite: inhalation solution.

Cardiovascular adverse events

Cardiovascular side effects manifesting as mild transitory headache, dizziness, and flushing of the face are common with the use of amyl nitrite. Hypotension, syncope, and tachycardia have also been reported.[Ref]

Nervous system

Nervous system side effects including cold sweats, pallor, restlessness, weakness, and involuntary passing of urine and feces have been reported.[Ref]

Gastrointestinal

Gastrointestinal side effects including vomiting and nausea have been reported.[Ref]

Hematologic

Hematologic side effects including methemoglobinemia associated with high doses of chronically administered amyl nitrite have been reported.[Ref]

References

1. (2004) "Product Information. Amyl Nitrite (amyl nitrite)." Raway Pharmacal Inc

Further information

Amyl nitrite side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer