Altretamine Side Effects
Medically reviewed by Drugs.com. Last updated on Oct 26, 2023.
Applies to altretamine: oral capsule.
Warning
You should not use altretamine if you have severe nerve problems or severe bone marrow suppression.
Altretamine can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often.
Altretamine can affect your nervous system. Call your doctor at once if you have severe dizziness, fainting, seizure, or severe numbness, tingling, or cold feeling in your hands or feet.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using altretamine and call your doctor at once if you have:
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severe numbness, tingling, or cold feeling in your hands or feet;
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severe or continuous vomiting;
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fever, chills, flu symptoms, mouth sores, pale skin, easy bruising or bleeding, unusual weakness;
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a light-headed feeling, like you might pass out;
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severe dizziness or spinning sensation;
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seizure (convulsions); or
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upper stomach pain, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects may include:
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mild nausea or vomiting;
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mild numbness or tingling;
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loss of appetite;
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mood changes, mild dizziness; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to altretamine: oral capsule.
Hematologic
Very common (10% or more): Anemia (33%)
Common (1% to 10%): Thrombocytopenia, leukopenia[Ref]
Gastrointestinal
Very common (10% or more): Nausea and vomiting (33%)
Common (1% to 10%): Increased alkaline phosphatase[Ref]
Nervous system
Very common (10% or more): Peripheral sensory neuropathy (31%)
Common (1% to 10%): Seizures
Frequency not reported: CNS symptoms (mood disorders, disorders of consciousness, ataxia, dizziness, vertigo)[Ref]
Renal
Common (1% to 10%): Increased BUN, increased serum creatinine[Ref]
Metabolic
Uncommon (0.1% to 1%): Anorexia[Ref]
Other
Uncommon (0.1% to 1%): Fatigue[Ref]
Hepatic
Frequency not reported: Hepatic toxicity[Ref]
Dermatologic
Frequency not reported: Skin rash, pruritus, alopecia[Ref]
More about altretamine
- Check interactions
- Compare alternatives
- Reviews (1)
- Dosage information
- During pregnancy
- Drug class: miscellaneous antineoplastics
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References
1. Product Information. Hexalen (altretamine). US Bioscience. 2022.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.