Adstiladrin Side Effects
Generic name: nadofaragene firadenovec
Medically reviewed by Drugs.com. Last updated on Mar 14, 2024.
Note: This document contains side effect information about nadofaragene firadenovec. Some dosage forms listed on this page may not apply to the brand name Adstiladrin.
Applies to nadofaragene firadenovec: urinary bladder suspension.
Serious side effects of Adstiladrin
Along with its needed effects, nadofaragene firadenovec (the active ingredient contained in Adstiladrin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking nadofaragene firadenovec:
More common
- Blood in the urine
- burning while urinating
- chills
- difficult or painful urination
- fever
- trouble in holding or releasing urine
- unusual tiredness or weakness
Less common
- Anxiety
- arm, back, or jaw pain
- blurred vision
- chest pain, discomfort, heaviness, or tightness
- cold sweats
- coma
- confusion
- cool, pale skin
- decreased urination
- depression
- dizziness
- dry mouth
- fainting
- fast or irregular heartbeat
- headache
- lightheadedness
- nausea
- nervousness
- nightmares
- rapid breathing
- seizures
- shakiness
- slurred speech
- sunken eyes
- sweating
- thirst
- trouble breathing
- wrinkled skin
Rare
- Dilated neck veins
- blue or pale skin
- irregular breathing
- problems with movement, walking, or speech
- swelling of the face, fingers, feet, or lower legs
- vomiting
- weight gain
For Healthcare Professionals
Applies to nadofaragene firadenovec: intravesical suspension.
General
The most common adverse reactions reported in 10% or more patients including laboratory abnormalities in more than 15% patients, were increased glucose, instillation site discharge, increased triglycerides, fatigue, bladder spasm, micturition (urination) urgency, increased creatinine, hematuria (blood in urine), decreased phosphate, chills, dysuria, and pyrexia (fever).[Ref]
Cardiovascular
Common (1% to 10%): Coronary artery disease, acute coronary syndrome, atrial fibrillation, heart failure, pericarditis[Ref]
Hematologic
Very common (10% or more): Decreased hemoglobin (16%)[Ref]
Metabolic
Very common (10% or more): Increased glucose (38%), increased triglycerides (30%), increased creatinine (17%), decreased phosphate (16%)
Common (1% to 10%): Dehydration, hypoglycemia, bile duct stone[Ref]
Other
Very common (10% or more): Instillation site discharge (33%), fatigue (24%), chills (16%), pyrexia (15%)
Common (1% to 10%): Syncope, sepsis[Ref]
Renal
Very common (10% or more): Bladder spasm (20%), micturition urgency (19%), hematuria (17%), dysuria (16%)[Ref]
Nervous system
Common (1% to 10%): Brain edema[Ref]
More about Adstiladrin (nadofaragene firadenovec)
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References
1. Product Information. Adstiladrin (nadofaragene firadenovec). Ferring Pharmaceuticals Inc. 2022.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.