Vasomotor Symptoms Linked to Increased Risk for Alzheimer Disease
Medically reviewed by Drugs.com.
By Elana Gotkine HealthDay Reporter
WEDNESDAY, Sept. 27, 2023 -- Vasomotor symptoms (VMS), especially during sleep, are associated with an increased risk for Alzheimer disease (AD), according to a study presented at the annual meeting of the North American Menopause Society, held from Sept. 27 to 30 in Philadelphia.
Rebecca C. Thurston, Ph.D., from the University of Pittsburgh, and colleagues enrolled 274 late perimenopausal or postmenopausal women aged 45 to 67 years who had a uterus and at least one ovary. Women underwent assessment of their VMS, and the association with adverse AD biomarker profiles was examined. Data for the analysis were contributed by 248 participants.
The researchers observed an association for objectively assessed VMS, especially sleep VMS, with significantly lower amyloid β (Aβ)42/40. An increased likelihood of being in the low/abnormal Aβ42/40 cluster was seen in association with a greater number of sleep VMS (odds ratio, 1.18). After additional adjustments for estradiol and actigraphy-assessed sleep duration and wake after sleep onset, the findings remained significant.
"Given the adverse effect on quality of life and financial burden of AD, it's important that we learn as much as possible about potential causes and warning signs so we can be proactive before the onset of AD," Stephanie Faubion, M.D., medical director of the North American Menopause Society, said in a statement. "This study underscores the need for ongoing open dialogues between patients and their health care professionals so that any treatment options can be carefully considered."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted September 2023
Read this next
Benzodiazepines Not Tied to Higher Dementia Risk in Older Adults
TUESDAY, July 16, 2024 -- Use of benzodiazepines is not associated with increased dementia risk in older adults, according to a study published online July 2 in BMC...
Metformin, SGLT2 Inhibitors Exhibit Significantly Lower Dementia Risk
MONDAY, July 15, 2024 -- Compared with other antidiabetic classes, metformin and sodium glucose co-transporter-2 inhibitors (SGLT2is) exhibit significantly lower dementia risk...
Nightmares in Midlife May Point to Future Cognitive Decline, Dementia
FRIDAY, July 12, 2024 -- Distressing dreams in middle-aged and older adults may indicate a higher risk for future cognitive decline and all-cause dementia, according to a study...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.