Urinary Cadmium Levels Linked to Cognitive Impairment in Whites
By Elana Gotkine HealthDay Reporter
WEDNESDAY, Sept. 4, 2024 -- Among White, but not Black individuals, urinary cadmium (Cd) concentrations are associated with cognitive impairment, according to a study published online Sept. 4 in Neurology.
Liping Lu, M.D., Ph.D., from the Mailman School of Public Health at Columbia University in New York City, and colleagues examined the association between urinary Cd concentration and cognitive impairment in a subcohort of REasons for Geographic and Racial Differences in Stroke study participants who were free of cognitive impairment or stroke at baseline.
The analyses included 2,172 participants with available data on urinary Cd concentration, including 195 cases of global cognitive impairment and 53 cases of domain-based cognitive impairment. In the full sample, the researchers observed no association between Cd and cognitive impairment, but a significant positive association of urinary Cd concentration with global cognitive impairment was seen among White but not Black participants. In the high versus low urinary Cd group, the odds of cognitive impairment for White participants were doubled (odds ratio, 2.07). The associations of interest were not materially modified by sex, age, region, smoking pack-years, alcohol consumption, or other related metals.
"These results need to be confirmed with studies that measure cadmium levels over time, include more people and follow people over a longer time, but there are many reasons to reduce exposure to cadmium, whether it's through implementing policies and regulations for air pollution and drinking water or people changing their behaviors by stopping smoking or being around cigarette smoke," Lu said in a statement.
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
![](/img/logo/vendor/healthday-logo.png)
© 2024 HealthDay. All rights reserved.
Posted September 2024
Read this next
Dementia Diagnoses Up in Individuals With Acute Kidney Injury
THURSDAY, Sept. 5, 2024 -- Individuals with acute kidney injury (AKI) have an increased risk for receiving a clinical diagnosis of dementia, according to a study published online...
SGLT-2 Inhibitors May Cut Dementia Risk in Patients With Diabetes
TUESDAY, Sept. 3, 2024 -- Sodium-glucose cotransporter-2 (SGLT-2) inhibitors may prevent dementia in middle-aged adults with diabetes, according to a study published online Aug...
Multiple Sclerosis Linked to Lower Risk for Alzheimer Disease Pathology
FRIDAY, Aug. 30, 2024 -- Multiple sclerosis (MS) is associated with a lower risk for Alzheimer disease, according to a study published in the September issue of the Annals of...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.