Study Reveals No Link Between HDL Cholesterol and Movement Disorders
By Lori Solomon HealthDay Reporter
FRIDAY, Sept. 20, 2024 – There is no correlation between high-density lipoprotein cholesterol (HDL-C) levels and a patient's risk for developing movement disorders while taking an antipsychotic, according to a study published in the April-June issue of Innovations in Clinical Neuroscience.
Carolyn O’Donnell, Pharm.D., from the Edward Hines Jr. Veterans Administration Hospital in Hines, Illinois, and colleagues investigated associations between patients taking antipsychotics with low HDL-C and the risk for developing a movement disorder. The analysis included 89 adult patients at an inpatient state psychiatric facility.
The researchers report that only eight patients had an Abnormal Involuntary Movement Scale score greater than 0 and HDL-C levels ranged from 17 mg/dL to 83 mg/dL. There was no statistically significant association seen when comparing a patient's movement disorder, Abnormal Involuntary Movement Scale scores, and HDL-C levels.
"It is our hope that our research will support prioritized prescribing decisions focused more directly on removing offending medications, versus exploring hypothesized physiologic factors such as HDL-C, because earlier recognition of drug-induced movement disorders permits rapid intervention and decreased risk of permanently disfiguring and debilitating extrapyramidal symptoms," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted September 2024
Read this next
Prevalence of High Total Cholesterol 11.3 Percent in U.S. Adults
WEDNESDAY, Nov. 20, 2024 -- The prevalence of high total cholesterol was 11.3 percent among U.S. adults in August 2021 to August 2023, according to a November data brief published...
Oral Microbiome Linked to Stress, Mental Health in Pregnant Women
WEDNESDAY, Nov. 20, 2024 -- In pregnant women, the oral microbiome is associated with stress and mental health, according to a study published online Nov. 19 in BMJ Mental...
Transcranial Direct Current Stimulation Safe, Effective for Tardive Dyskinesia
MONDAY, Nov. 18, 2024 -- Transcranial direct current stimulation (tDCS) may be an effective and safe treatment for improving the facial-oral motor symptoms of tardive dyskinesia...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.