Disease Severity Similar for RSV as Unvaccinated COVID-19, Influenza
By Elana Gotkine HealthDay Reporter
FRIDAY, April 5, 2024 -- Disease severity is similar for patients hospitalized with respiratory syncytial disease (RSV) and unvaccinated adults with COVID-19 or influenza, according to a study published online April 4 in JAMA Network Open.
Diya Surie, M.D., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues examined disease severity among adults hospitalized with RSV and compared it to the severity of COVID-19 and influenza disease in a cohort study. A total of 7,998 adults admitted to the hospital with acute respiratory illness and laboratory-confirmed RSV, severe acute respiratory syndrome coronavirus 2, or influenza infection (6.1, 80.3, and 13.7 percent, respectively) were prospectively enrolled from 25 hospitals between Feb. 1, 2022, and May 31, 2023.
The researchers found that 12.0 percent of patients with RSV experienced invasive mechanical ventilation (IMV) or death compared with 14.2 and 9.2 percent, respectively, of unvaccinated and vaccinated patients with COVID-19 and 10.3 and 5.1 percent, respectively, of unvaccinated and vaccinated patients with influenza. The odds of IMV or in-hospital death were not significantly different for patients hospitalized with RSV and unvaccinated patients hospitalized with COVID-19 or influenza in adjusted analyses; the odds of IMV or death were significantly elevated among patients hospitalized with RSV versus vaccinated patients hospitalized with COVID-19 or influenza (adjusted odds ratios, 1.38 and 2.81, respectively).
"Newly approved RSV vaccines for adults aged 60 years and older have the potential to reduce this severity, similar to attenuation of disease severity achieved with COVID-19 and influenza vaccination, as previously reported and also observed in this analysis," the authors write.
Several authors disclosed ties to the biopharmaceutical industry; one author disclosed a patent for an airway device.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted April 2024
Further Support and Information on COVID-19
Read this next
COVID-19 Vaccination Not Tied to Adverse Pregnancy Outcomes
TUESDAY, June 25, 2024 -- mRNA COVID-19 vaccination during pregnancy is not associated with an increased risk of adverse pregnancy outcomes, according to a study published in the...
Cannabis Use Tied to Risk of COVID-19 Hospitalizations, ICU Admissions
TUESDAY, June 25, 2024 -- Current cannabis use may be an independent risk factor for COVID-19–related complications, according to a study published online June 21...
Maternal Distress Tied to Changes in Brain Growth of Offspring
FRIDAY, June 21, 2024 -- Regional neonatal brain volumes are associated with elevated maternal psychological distress, according to a study published online June 20 in JAMA...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.