Rates of Sexual Dysfunction High in Patients With Schizophrenia
Medically reviewed by Drugs.com.
By Lori Solomon HealthDay Reporter
FRIDAY, Sept. 15, 2023 -- There is a high prevalence of sexual dysfunction among individuals with schizophrenia, according to a review published online Sept. 13 in JAMA Psychiatry.
Théo Korchia, M.D., from Aix-Marseille University in France, and colleagues conducted a systematic literature review and meta-analysis to assess sexual dysfunction and associated factors in individuals with schizophrenia-spectrum disorders.
Based on 72 studies (33 countries and 21,076 participants with schizophrenia), the researchers found that the pooled global prevalence of sexual dysfunctions was 56.4 percent (55.7 percent for men and 60.0 percent for women). In men, the most frequent sexual dysfunction was erectile dysfunction (44 percent), loss of libido (41 percent), and ejaculation dysfunction (39 percent). In women, the most common dysfunctions were orgasm dysfunction (28 percent) and amenorrhea (25 percent). Sexual dysfunctions were seen more frequently in patients with schizophrenia compared with patients with schizoaffective disorders. Erectile disorders were less frequent in individuals with longer illness duration. Lower rates of erectile disorders were associated with antidepressant and mood stabilizer prescriptions, as were ejaculation disorders.
"The findings in this study suggest that prevalence of sexual dysfunction remains high in people with schizophrenia with no obvious improvement over time or better tolerance of second-generation antipsychotics," the authors write. "Treating depression may be a key point to reduce sexual dysfunction in individuals with schizophrenia."
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted September 2023
Read this next
Transgender, Gender-Diverse Adults Face Higher Risk for Experiencing Violence
TUESDAY, July 2, 2024 -- Transgender and gender-diverse individuals have a higher risk for experiencing all forms of violence compared with cisgender women, according to a study...
Health Status, Mental Health Worsened in U.S. Transgender Adults From 2014 to 2022
TUESDAY, June 25, 2024 -- Health status, mental health, and health inequities worsened in the United States from 2014 to 2022 among transgender (TGD) adults, according to a...
SNP rs13194504 AA Genotype Linked to Severity of Tardive Dyskinesia
TUESDAY, June 25, 2024 -- For patients with schizophrenia, the single-nucleotide polymorphism (SNP) rs13194504 AA genotype is associated with reduced severity of tardive...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.