Rate of Twin Births Increased in Pregnancies With Higher BMI
By Lori Solomon HealthDay Reporter
FRIDAY, Jan. 12, 2024 -- The rate of twin deliveries increased with increasing body mass index (BMI), and part of this association was explained by higher use of assisted reproductive technology (ART), according to a study published online Jan. 9 in JAMA Network Open.
Jeffrey N. Bone, from the University of British Columbia in Vancouver, Canada, and colleagues examined the association between BMI and twin birth and the role of ART as a potential mediator in this association. The analysis included 392,046 deliveries (gestational age of ≥20 weeks) with complete data identified from the British Columbia Perinatal Database Registry (2008 to 2020).
The researchers found that when adjusting for other covariates, women with underweight had relatively fewer twins compared with women with normal BMI (adjusted risk ratio [aRR], 0.84), while women with overweight, class I obesity, class II obesity, and class III obesity had higher rates (aRRs, 1.14, 1.16, 1.17, 1.41, respectively). Additionally, the proportion of women who conceived by ART increased with increasing BMI. ART was associated with a substantially higher rate of twin delivery (aRR, 11.80) and explained about one-quarter of the association between obesity class I and II and twin delivery (e.g., obesity class I, 23 percent mediated).
"We found a relatively small excess of twin deliveries in women who had overweight and obesity prior to pregnancy compared with women with normal BMI," the authors write.
One author disclosed ties to the pharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted January 2024
Read this next
Small Differences in Weight Change With First-Line Antidepressants
MONDAY, July 1, 2024 -- For eight first-line antidepressants, small differences are seen in mean weight change, with the least weight gain with bupropion, according to a study...
Bariatric Surgery Tied to Lower Risk of MACE, Death in Obesity, Sleep Apnea
FRIDAY, June 28, 2024 -- Metabolic surgery is associated with significantly lower risk of major adverse cardiovascular events (MACE) compared with nonsurgical management among...
Exercise + GLP-1 RA Effective for Weight Loss While Preserving BMD
THURSDAY, June 27, 2024 -- For adults with obesity, without diabetes, combining exercise with the glucagon-like peptide-1 receptor agonist (GLP-1 RA), liraglutide, is effective...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.