Psychological Well-Being Declines Years Before Diagnosis of MCI
By Lori Solomon HealthDay Reporter
TUESDAY, Aug. 20, 2024 -- Psychological well-being can significantly decline years before a diagnosis of mild cognitive impairment (MCI), regardless of the ultimate development of dementia, according to a study published online Aug. 13 in the Journal of Neurology, Neurosurgery & Psychiatry.
Jie Guo, from China Agricultural University in Beijing, and colleagues explored psychological well-being trajectories before and after the diagnosis of MCI and dementia. The analysis included 910 cognitively intact older adults participating in the Rush Memory and Aging Project, with annual follow-up for up to 14 years.
The researchers found that compared with participants who remained cognitively intact, those who developed incident MCI had a faster decline in psychological well-being (β, −0.015), with lower well-being two years before MCI diagnosis. Among those who developed MCI, lower levels of purpose in life and personal growth were detected three years (−0.126) and six years (−0.139) before MCI, respectively. Except for positive relations with others, the slope of psychological well-being decline was similar before and after MCI diagnosis for other components. Well-being trajectories were similar for MCI regardless of whether individuals later developed dementia.
"Reduced psychological well-being, even in the absence of evident cognitive impairment, may serve as a predictor for impaired cognitive function, and postdiagnostic psychological support should be planned for people diagnosed with dementing disorders," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted August 2024
Read this next
Inflammation in Childhood Linked to Onset of Mental Health Disorders
FRIDAY, Aug. 23, 2024 -- Low-grade systemic inflammation across childhood and adolescence is associated with the subsequent onset of mental health disorders, according to a study...
Cognitive Difficulties Tied to Lower Return to Work After Breast Cancer
FRIDAY, Aug. 23, 2024 -- Return to work two years after a breast cancer diagnosis is associated with higher cognitive speed performance before and after treatment, according to a...
Child Maltreatment, Particularly Neglect, Tied to Cognitive Deficits
WEDNESDAY, Aug. 21, 2024 -- Childhood maltreatment is associated with later cognitive difficulties, according to a study published in the September issue of The Lancet...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.