Preeclampsia Linked to Increased Risk for Young-Onset Dementia
By Elana Gotkine HealthDay Reporter
FRIDAY, May 31, 2024 -- Individuals with preeclampsia have an increased risk for young-onset dementia, according to a research letter published online May 30 in JAMA Network Open.
Valérie Olié, Ph.D., from Santé Publique in Saint-Maurice, France, and colleagues obtained data from the nationwide prospective Conception study, which included all deliveries in France after 22 weeks of gestation between Jan. 1, 2010, and Dec. 31, 2018. Individuals aged 30 years or older without a history of dementia were identified and followed from delivery to Dec. 31, 2021; the analyses included 1,966,323 individuals, <1 percent of whom developed dementia.
Dementia was identified using the primary diagnosis for hospitalization during 9.0 years of mean follow-up. The researchers found that compared with pregnancy without hypertensive disorders of pregnancy, preeclampsia was associated with an increased risk for young-onset dementia (hazard ratio, 2.65). When preeclampsia occurred before 34 weeks of gestation or was superimposed on chronic hypertension, the risk for young-onset dementia was even higher (hazard ratios, 4.15 and 4.76, respectively). Severe preeclampsia was not associated with young-onset dementia.
"The results add early-onset preeclampsia to the list of lifelong disease risks or health care implications of having had preeclampsia," the authors write.
One author disclosed ties to the biopharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted May 2024
Read this next
Web-Based Cognitive Behavioral Therapy Aids Bulimia Outcomes
THURSDAY, July 18, 2024 -- A web-based, cognitive behavioral self-help intervention effectively cuts bulimia nervosa symptoms, according to a study published online July 3...
Calcium, Zinc Intake Tied to Lower Risk for Hypertensive Disorders of Pregnancy
TUESDAY, July 16, 2024 -- People with higher intakes of calcium and zinc before pregnancy appear to have a significantly lower risk for hypertensive disorders of pregnancy (HDP)...
Benzodiazepines Not Tied to Higher Dementia Risk in Older Adults
TUESDAY, July 16, 2024 -- Use of benzodiazepines is not associated with increased dementia risk in older adults, according to a study published online July 2 in BMC...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.