Poor Mental Health Outcomes More Likely With Hyperemesis Gravidarum
FRIDAY, Sept. 26, 2025 -- Hyperemesis gravidarum is associated with an increased risk for poorer mental health outcomes compared with pregnancy without hyperemesis gravidarum, according to a study published online Sept. 18 in The Lancet Obstetrics, Gynaecology, & Women's Health.
Hamilton Morrin, M.B.B.S., from King's College London, and colleagues conducted a retrospective cohort study of anonymized electronic medical records to examine the relative risks for incident neuropsychiatric and mental health outcomes during the first year following a hyperemesis gravidarum diagnosis. A total of 476,857 pregnant women in the TriNetX database were diagnosed with hyperemesis gravidarum across 135 health care providers in 18 high-income and middle-income countries; they were matched with a control cohort of women with pregnancy coding without hyperemesis gravidarum.
The researchers found significant relative risks for 18 of 24 outcomes, with the five greatest relative risks for Wernicke encephalopathy, refeeding syndrome, postpartum depression, eating disorders, and antipsychotic prescription (2.39, 2.57, 2.70, 2.06, and 2.23, respectively). There was a reduction in the risk for termination of pregnancy (0.77). For nonaffective psychoses, bipolar affective disorder, intentional self-harm, and suicide attempt, no association was observed.
"[Hyperemesis gravidarum] can be associated with severe psychiatric disorders that require urgent recognition and joined-up physical and mental health care from the very start of pregnancy," senior author Thomas A. Pollak, Ph.D., also from King's College London, said in a statement.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Read this next
AAP: Pediatric Golf Cart-Related Injuries Mainly Caused by Falls
TUESDAY, Sept. 30, 2025 -- Pediatric/young adult golf cart-related injuries are mainly caused by falls from the golf cart, according to a study presented at the annual meeting of...
Study Chronicles War-Related Injuries in Gaza
TUESDAY, Sept. 30, 2025 -- A special article published online Sept. 25 in The BMJ chronicles war-related injuries seen in Gaza. Omar El-Taji, a research fellow from...
Self-Reported Cognitive Disability Rates Increased in U.S. Adults From 2013 to 2023
TUESDAY, Sept. 30, 2025 -- Rates of self-reported cognitive disability rose in U.S. adults from 5.3 to 7.4 percent in the last decade, particularly among younger adults, according...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.