Skip to main content

Micronized Amnion/Chorion Aids Interstitial Cystitis/Bladder Pain Syndrome

Medically reviewed by Carmen Pope, BPharm. Last updated on Oct 31, 2024.

By Lori Solomon HealthDay Reporter

THURSDAY, Oct. 31, 2024 -- Injected micronized amnion/chorion bilayer (AC) product significantly reduces time to symptom relief in patients with refractory interstitial cystitis/bladder pain syndrome (IC/BPS), according to a study published online Oct. 23 in International Urology & Nephrology.

Kyle O’Hollaren, from Wayne State University School of Medicine in Detroit, and colleagues evaluated the therapeutic responses and adverse events of micronized AC in patients with refractory IC/BPS. The analysis included 15 patients who failed conventional therapy and received 100 mg of reconstituted micronized AC injected intra-detrusor via cystoscopy under general anesthesia using a 23-gauge needle. Twenty 0.5-mL injections were administered into the lateral and posterior bladder walls with outcomes evaluated at six months.

The researchers found that one month after injections, there was significant improvement in IC/BPS symptom scores in all patients. At six months postinjection, all patients maintained a sustained clinical response. There were no product-related adverse events observed.

"These results suggest a promising clinical benefit of using an amnion/chorion bilayer product for treating IC/BPS," the authors write. "Further research is needed to confirm these findings and assess the long-term durability of this treatment approach. This study represents the first evidence supporting the clinical advantages of an amnion/chorion bilayer product in managing IC/BPS."

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Posted October 2024

Read this next

Lower Oral Health Scores Linked to Higher Pain Scores in Women

MONDAY, April 14, 2025 -- Low oral health scores are associated with higher pain scores, including migraine headache, among women, according to a study published online April 9 in...

ACP: Guidance Provided for Use of Cannabis in Chronic Noncancer Pain Management

MONDAY, April 7, 2025 -- In a best practice guideline issued by the American College of Physicians and published online April 4 in the Annals of Internal Medicine, advice is...

Evidence Supports Continuing Buprenorphine for Acute Pain in Those With Opioid Use Disorder

MONDAY, March 31, 2025 -- For patients with opioid use disorder (OUD), evidence supports continuation of buprenorphine during episodes of acute pain, but overall evidence for pain...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.