Metabolic, Bariatric Surgery Provides Pathway to Transplant in ESRD
By Elana Gotkine HealthDay Reporter
TUESDAY, March 12, 2024 -- Referral of obese end-stage renal disease (ESRD) patients to metabolic and bariatric surgery (MBS) could offer a pathway to transplant, according to a study published online March 12 in the Journal of the American College of Surgery.
Noting that an elevated body mass index is a major cause of transplant preclusion in ESRD, Shauna Levy, M.D., from the Tulane University School of Medicine in New Orleans, and colleagues created a collaborative program for ESRD patients to undergo weight loss before obtaining a kidney transplant. A total of 183 patients were referred to the bariatric team by the transplant team; 36 underwent MBS (20 Roux-en-Y gastric bypass; 16 sleeve gastrectomy). Of these, 10 underwent subsequent transplantation and 15 are currently wait-listed.
The mean body mass index was 46.4 kg/m2 at the start and 33.9 kg/m2 at the time of transplant. The researchers observed a reduction in the average number of hypertension mediations from 2.0 to 1.0 presurgery to postsurgery, respectively. Similarly, improvement was seen in hemoglobin A1c levels, from 6.2 preoperatively to 5.2 postoperatively. All transplants are currently functioning, with median creatinine of 1.5 mg/dL.
"A collaborative effort with an MBS and transplant team offers a pathway for morbidly obese ESRD candidates who would otherwise be denied a transplant," the authors write. "With increasing prevalences of obesity and ESRD in this country, we see this as a growing issue."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
![](/img/logo/vendor/healthday-logo.png)
© 2024 HealthDay. All rights reserved.
Posted March 2024
Read this next
Small Differences in Weight Change With First-Line Antidepressants
MONDAY, July 1, 2024 -- For eight first-line antidepressants, small differences are seen in mean weight change, with the least weight gain with bupropion, according to a study...
Few With Type 2 Diabetes Receive Guideline-Recommended CKD Screening
MONDAY, July 1, 2024 -- Fewer than one-quarter of patients with type 2 diabetes (T2D) receive recommended chronic kidney disease (CKD) screening, according to a study published...
Bariatric Surgery Tied to Lower Risk of MACE, Death in Obesity, Sleep Apnea
FRIDAY, June 28, 2024 -- Metabolic surgery is associated with significantly lower risk of major adverse cardiovascular events (MACE) compared with nonsurgical management among...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.