Generalized Joint Hypermobility May Increase Risk for Long COVID
By Lori Solomon HealthDay Reporter
TUESDAY, March 26, 2024 -- The presence of generalized joint hypermobility (GJH) is associated with not recovering fully from COVID-19, according to a study published online March 19 in BMJ Public Health.
Jessica A. Eccles, M.B.Ch.B., Ph.D., from Brighton and Sussex Medical School in the United Kingdom, and colleagues evaluated whether GJH is a risk factor for self-reported nonrecovery from COVID-19. The analysis included participants in the COVID Symptom Study Biobank who were surveyed in 2022 (3,064 with at least one infection with COVID-19).
The researchers found that the presence of GJH was not specifically associated with reported COVID-19 infection but was significantly associated with nonrecovery from COVID-19 (odds ratio [OR], 1.43). After sequential models adjusting for age, sex, ethnic group, education level, and index of multiple deprivation, this association remained significant (OR, 1.33) and persisted with further adjustment for vaccination status and number of vaccinations (OR, 1.33). Hypermobility significantly predicted higher fatigue levels (B = 0.95). The association between GJH and nonrecovery from COVID-19 was mediated by fatigue levels (estimate of indirect effect, 0.18).
"This observation is clinically important through its potential impact for understanding and identifying sub-phenotypes of long COVID for screening and personalized targeted interventions," the authors write.
One author disclosed a consultancy contract with ZOE Ltd.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted March 2024
Further Support and Information on COVID-19
Read this next
Psoriasis, With or Without Psoriatic Arthritis, Associated With Fatigue
MONDAY, July 1, 2024 -- Psoriasis is associated with fatigue, especially among those with psoriatic arthritis (PsA), according to a study published in the July issue of the...
RA Patients With Mono-, Oligo-Arthritis, High PGA Remain Most Fatigued
FRIDAY, June 28, 2024 -- Rheumatoid arthritis (RA) patients with mono- or oligo-arthritis and high Patient Global Assessment (PGA) at diagnosis remain the most fatigued, according...
Fatigue With Rheumatoid Arthritis Tied to Disease Activity, Education Level
WEDNESDAY, June 26, 2024 -- The Bristol Rheumatoid Arthritis Fatigue Multi-Dimensional Questionnaire (BRAF-MDQ) and Brief Fatigue Inventory (BFI-C) scores show consistency in...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.