Extracorporeal Shock-Wave Lithotripsy, Endoscopy Beneficial for Pancreatitis
By Elana Gotkine HealthDay Reporter
TUESDAY, May 28, 2024 -- For patients with chronic pancreatitis and intraductal stones, combined extracorporeal shock-wave lithotripsy (ESWL) and endoscopic retrograde pancreatography (ERP) provides pain relief at 12 weeks, according to a study published online May 28 in the Annals of Internal Medicine.
Rupjyoti Talukdar, M.D., from the Asian Institute of Gastroenterology in Hyderabad, India, and colleagues examined the pain-relieving effect of pancreatic duct decompression in 106 patients with chronic pancreatitis and intraductal stones. Combined ESWL and ERP were compared to sham procedures (52 and 54 patients, respectively); the primary end point was pain relief at 12 weeks.
The researchers found that the ESWL/ERP group showed better pain relief than the sham group at 12 weeks (mean difference in change, −0.7 on the visual analog scale). At the 24-week follow-up, the difference between the groups was not sustained; no differences were seen between the groups in 30 percent pain relief at 12- or 24-week follow-up. Compared with the sham group, in the ESWL/ERP group, there was an increase in the number of pain-free days (median difference, 16.2 days) and a reduction in the number of days using opioids (median difference, −5.4 days) at 12-week follow-up. The groups had similar safety outcomes.
"Compared with a sham procedure, pancreatic ductal clearance using combined ESWL/ERP provided modest short-term pain relief in patients with chronic pancreatitis and intraductal stones," the authors write.
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
![](/img/logo/vendor/healthday-logo.png)
© 2024 HealthDay. All rights reserved.
Posted May 2024
Read this next
Pancreatic Enzyme Therapy Linked to Drop in Pediatric Acute Pancreatitis
TUESDAY, April 16, 2024 -- Use of pancreatic enzyme therapy (PERT) is associated with a reduction in the incidence rate of acute pancreatitis (AP) among children with pancreatic...
Evidence-Based Approach Recommended for Acute Pancreatitis Management
MONDAY, March 18, 2024 -- In a clinical guideline issued by the American College of Gastroenterology and published online in the March issue of the American Journal of...
GI Adverse Events Increased With Use of GLP-1 Agonists for Weight Loss
FRIDAY, Oct. 6, 2023 -- Use of glucagon-like peptide 1 (GLP-1) receptor agonists for weight loss is associated with increased risks for pancreatitis, gastroparesis, and bowel...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.